Evidence and Research

Trials have shown that daily oral PrEP works if taken correctly and consistently. But there’s still a lot to learn about new PrEP agents and how to deliver oral PrEP.


PrEP research today spans implementation research on delivering daily oral tenofovir-based PrEP and clinical trials of new agents, including vaginal ARV-containing rings and long-acting injectables. Policy and program decisions are guided by data from the original randomized clinical trials as well as newer studies. There are many moving pieces and many product types.

No single PrEP option—and no single prevention option—is right for all people, or for any one person all the time. Demonstration projects are providing information about what's available, even as research continues for additional options.

Read below to find out more about:

Clinical Trials Evidence
Open Label and Demonstration Project Evidence
Ongoing Research

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