Clinical Guidelines for PrEP
Clinical guidelines provide detailed information to providers for delivering PrEP effectively. Documents listed below include comprehensive guidelines on use of ART for treatment and prevention.
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World Health Organization
- WHO Implementation Tool for Pre-Exposure Prophylaxis (PrEP) of HIV Infection - The WHO has developed this series of modules to support the implementation of PrEP among a range of populations in different settings, including detailed clinical guidelines.
- Handbook of the Botswana 2016 Integrated HIV Clinical Care Guidelines – recommends PrEP for anyone at “high-risk”.
- Canadian Guideline on HIV Pre-exposure Prophylaxis and Nonoccupational Postexposure Prophylaxis (2017) – This guideline recommends oral PrEP for adults who are at high, ongoing risk of infection.
- Guidelines on Use of Antiretroviral Drugs for Treating and Preventing HIV Infection (2018) – Guidelines from the National AIDS & STI Control Program (NASCOP) on ARVs for treating and preventing HIV. PrEP is recommend for HIV negative individuals at substantial ongoing risk of HIV infection.
- National Guidelines on the Use of Antiretroviral Therapy For HIV Prevention and Treatment (2016) - These guidelines recommend oral PrEP for HIV-negative individuals at ‘significant risk’ of becoming infected with HIV.
- National Guidelines For HIV Prevention, Treatment and Care - It is recommended that pre-exposure prophylaxis (PrEP) should be offered as an additional prevention choice for HIV negative persons who are exposed to prolonged and substantial risk of acquiring HIV infection as a part of a combination of other available HIV prevention methods.
- South African Guidelines on the Safe Use of Pre-exposure Prophylaxis in Persons at Risk of Acquiring HIV-1 Infection (2016) – The aim of these guidelines is to explain what PrEP is; outline indications for its use; outline steps for appropriate user selection; provide guidance to monitor and maintain PrEP users.
- Consolidated Guidelines for Prevention and Treatment of HIV in Uganda (2018) - These guidelines recommend PrEP be offered to HIV-negative people at substantial risk of acquiring HIV infection.
- BHIVA/BASHH Guidelines on the Use of HIV Pre-Exposure Prophylaxis (2018) - This guideline recommends oral PrEP for adults who are at high, ongoing risk of infection.
- CDC Clinical Practice Guidelines (2017) – Comprehensive information for the use of daily oral antiretroviral preexposure prophylaxis (PrEP) to reduce the risk of acquiring HIV infection in adults.
- Consolidated Guidelines for Treatment & Prevention of HIV Infection (2018) – National strategy to combat HIV/AIDS, includes guidance on oral PrEP.
- Guidelines for Antiretroviral Therapy for the Prevention and Treatment of HIV in Zimbabwe (2016) - These guidelines recommend Pre-Exposure Prophylaxis (PrEP) which should be offered as an additional prevention choice for people at substantial risk of HIV infection as part of combination prevention approaches.