The Global Evaluation of Microbicide Sensitivity (GEMS) monitors HIV drug resistance (HIVDR) in PrEP seroconverters in project-based and national roll-out programs in sub-Saharan Africa. GEMS activities include:
- Laboratory research to improve HIVDR testing assays and test diverse sample types for HIVDR using sensitive methods.
- Modeling to evaluate the impact of HIVDR on PrEP and antiretroviral treatment (ART) strategies.
- Technical support and policy guidance for HIVDR assessment in seroconverters to PrEP programs.
- Implementation of HIVDR monitoring strategies in select countries in sub-Saharan Africa.
GEMS developed toolkit materials to assist ministries of health, project implementers and policy makers develop HIVDR monitoring strategies and support the collection and testing of blood samples for HIVDR testing.