National Policies and Guidelines for PrEP
Country-specific policies and guidelines provide detailed information for delivering PrEP effectively in a given context. Documents listed below include comprehensive national guidelines on use of ART for treatment and prevention as well as additional implementation and provider- and stakeholder-specific tools.
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- Handbook of the Botswana 2016 Integrated HIV Clinical Care Guidelines – recommends PrEP for anyone at “high-risk”.
- Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis (2017)
- Guidance for the use of Pre-Exposure Prophylaxis (PrEP) for the prevention of HIV acquisition in British Columbia (2017)
- Quebec Ministry of Health and Social Services (2019) [French only]
- Guidelines on Use of Antiretroviral Drugs for Treating and Preventing HIV Infection (2018) – Guidelines from the National AIDS & STI Control Program (NASCOP) on ARVs for treating and preventing HIV. PrEP is recommend for for HIV negative individuals at substantial ongoing risk of HIV infection.
- HIV Prevention Revolution Roadmap - This road map proposes that high impact, evidence-based interventions should be sustained and targeted towards Counties and different population needs. It emphasizes the need for efficient delivery of combination prevention packages, synergistic integration of biomedical, behavioural and structural interventions and sustainable investment in HIV prevention research to sharply reduce the annual number of new HIV infections—from an estimated 101,560 in 2013 to near zero in 2030.
- PrEP Implementation Framework - The National AIDS & STI Control Program (NASCOP) published this framework to provide guidance on the rollout of PrEP in Kenya (launched in May 2017).
- National Guidelines on the Use of Antiretroviral Therapy For HIV Prevention and Treatment (2016) - These guidelines recommend oral PrEP for HIV-negative individuals at ‘significant risk’ of becoming infected with HIV.
- National Guidelines For HIV Prevention, Treatment and Care - It is recommended that pre-exposure prophylaxis (PrEP) should be offered as an additional prevention choice for HIV negative persons who are exposed to prolonged and substantial risk of acquiring HIV infection as a part of a combination of other available HIV prevention methods.
- National Strategic Plan for HIV, TB and STIs 2017-2022 – This is the fourth National Strategic Plan (NSP) that South Africa has adopted to guide its response to HIV, Tuberculosis and sexually transmitted infections. It was published by the South African National AIDS Council (SANAC).
- National Policy on HIV PrEP and Test and Treat (2016) - In June 2016 the South African National Department of Health (NDoH) rolled out oral PrEP to select sex workers sites. At that time, the guidelines were specific for the sex worker rollout. These guidelines have now been updated to include additional target populations, including men who have sex with men, serodiscordant couples, and adolescent girls and young women. The inclusion of these additional target populations in the PrEP rollout will be at the direction of the NDoH, over time, targeting prioritized populations in phased approaches.
- National Sex Worker HIV Plan (2016-2019) – Sets plan to ensure that at least 95% of sex worksers use condoms with clients and partners, gender-based violence falls by 50 percent, and the 90-90-90 targets are met for sex workers. The plan includes the provision of PrEP.
- South African Guidelines on the Safe Use of Pre-exposure Prophylaxis in Persons at Risk of Acquiring HIV-1 Infection (2016) – The aim of these guidelines is to explain what PrEP is; outline indications for its use; outline steps for appropriate user selection; provide guidance to monitor and maintain PrEP users.
- Consolidated Guidelines for Prevention and Treatment of HIV in Uganda (2018) - These guidelines recommend PrEP be offered to HIV-negative people at substantial risk of acquiring HIV infection.
- BHIVA/BASHH Guidelines on the Use of HIV Pre-Exposure Prophylaxis (2018)
- Scottish Medicines Consortium Truvada Assessment (2017)
- National HIV/AIDS Strategy for the United States (2015 – 2020) – The nation’s comprehensive strategy for HIV/AIDS prevention and treatment
- CDC Clinical Practice Guidelines (2017) – Comprehensive information for the use of daily oral antiretroviral preexposure prophylaxis (PrEP) to reduce the risk of acquiring HIV infection in adults
- CDC Providers’ Supplement (2014) – This supplement to the PHS PrEP Clinical Practice Guidelines is intended to provide additional information that may be useful to clinicians providing PrEP
- American College of Obstetricians and Gynecologists' guidance on PrEP for the Prevention of HIV (2014)
- The New York State Department of Health AID Institute guidance (2014) – The AIDS Institute Office of the Medical Director oversees development and dissemination of the clinical practice guidelines. Guidelines are developed by committees of clinical practice experts from all major regions of the state and from a variety of clinical care settings to ensure that recommendations are broadly applicable
- Gilead Physician Guidance (2013) – Is a “Risk Evaluation and Mitigation Strategy” (REMS) Web site for oral Truvada for PrEP
- Introducing the “PrEP Package” for Enhanced HIV Prevention: A Practical Guide for Clinicians - The Fenway Institute (2012)
- Consolidated Guidelines for Treatment & Prevention of HIV Infection (2018) – National strategy to combat HIV/AIDS, includes guidance on oral PrEP
- Guidelines for Antiretroviral Therapy for the Prevention and Treatment of HIV in Zimbabwe (2016) - These guidelines recommend Pre-Exposure Prophylaxis (PrEP) which should be offered as an additional prevention choice for people at substantial risk of HIV infection as part of combination prevention approaches