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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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7 April 2025

A Systematic Literature Review on Pre-exposure Prophylaxis as a Strategy for HIV Risk Reduction in the Middle East

This article from Cureus describes the results of a literature review to evaluate PrEP’s value and effectiveness in the Middle East and North Africa region and to develop targeted recommendations for overcoming barriers and expanding PrEP programs to better serve the region’s specific needs and populations at risk.

Research

External Link
31 March 2025

PrEP-it

Stakeholders at the forefront of oral PrEP delivery have encountered several programmatic challenges such as difficulty in setting targets, tracking the continuum of PrEP delivery, and estimating program costs and impact. In response, PEPFA) has developed a Microsoft Excel-based tool called PrEP-it for oral PrEP implementation planning, monitoring and evaluation.

Financing & Costing, Monitoring & Evaluation, Research, Service Delivery, Supply Chain Management

External Link
21 March 2025

UNAIDS: Impact of US Funding Cuts on the Global AIDS Response

This website, run by UNAIDS, tracks the impact of US government funding cuts on HIV services, and includes weekly situation reports and country profiles.

Monitoring & Evaluation, Research, Service Delivery

External Link
18 March 2025

Frozen Out: Impact of the PEPFAR funding freeze on programs for key populations

This report, developed by Global Black Gay Men Connect (GBGMC) and amfAR, analyses the impact of PEPFAR funding freezes on key populations worldwide, and provides recommendations on a way forward. For live tracking of this impact, see GBGMC’s Tracking the Freeze: Real-Time Impact on Key Populations.

Community/Advocacy, Financing & Costing, Research, Service Delivery

External Link
18 March 2025

A Health Systems Approach to More Effective Decentralised HIV Prevention: Development of Malawi’s Blantyre Prevention Strategy

This article from BMJ Global Health provides background on and shares the experiences of the Blantyre Prevention Strategy (BPS), a health systems-based approach to HIV prevention that directs investments towards embedding essential functions within Blantyre City and District in Malawi. The approach includes developing district-led systems and capabilities in effective disease surveillance and data-driven targeting,…

Demand Creation/Marketing, Research, Service Delivery

External Link
14 March 2025

Developing and Introducing a Dual Prevention Pill- Oral PrEP & oral contraception for HIV and pregnancy prevention

A coalition of partners is developing a novel Dual Prevention Pill (DPP) for prevention of pregnancy and HIV acquisition in high-need countries. In East and Southern Africa — where the DPP is initially planned for introduction — 65 percent of new HIV infections are amongst women aged 15 and over, and 15 percent of women…

Community/Advocacy, Research

Document
3 March 2025

Integrating HIV Prevention with Family Planning Services for Adolescent Girls and Young Women in Uganda: Perspectives of adolescent girls and young women, health care providers, and policymakers

This article from Frontiers in Reproductive Health discusses the results of a study examining various enablers and barriers to the successful integration of HIV prevention into family planning services in the areas of policy, human resources and infrastructure, resource management, service delivery, community involvement, supply chain management, and monitoring and reporting, and provides insights to…

Research, Service Delivery

External Link
3 March 2025

HIVR4P 2024 Knowledge Toolkit

The HIVR4P 2024 Knowledge Toolkit highlights important scientific advancements and innovative research across key thematic areas presented at the HIVR4P 2024 conference. Thematic areas include the PURPOSE 2 trial of long-acting lenacapavir for PrEP, data on the three-month dapivirine vaginal ring, and early evidence on offering a choice of PrEP methods.

Research

External Link
3 March 2025

Control of HIV across the WHO European Region: Progress and remaining challenges

This review from The Lancet Regional Health- Europe summarizes the barriers, opportunities, and pathways towards improvement of the HIV response in the WHO European region, including use of PrEP.

Monitoring & Evaluation, Research

External Link
3 March 2025

Preventing HIV in Women in Africa

This article from Nature Medicine discusses the evolving landscape of biomedical prevention technologies for women in Africa, their implementation and financing, as well as priorities for HIV prevention research in this setting.

Research

External Link