Integrating Long-acting Injectable Cabotegravir for HIV Prevention into the Brazilian Public Health System (ImPrEP CAB Brasil): A hybrid type-2 implementation-effectiveness cohort study

12 November 2026

This article from the Lancet HIV describes the results of the IMPrEP CAB Brasil study, which evaluated the feasibility of integrating same-day injectable cabotegravir delivery within the Brazilian public health system.

Featured Resources

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Now What with Injectable LEN for PrEP

This document, developed by Access Bridge and AVAC, outlines the current progress with rollout of injectable lenacapavir and what needs to happen next.

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Key considerations: Long-acting PrEP introduction

This document, developed under the EpiC and RISE projects, draws on early lessons to outline key considerations for HIV programs to accelerate long-acting PrEP introduction and scale-up while ensuring access to all individuals at risk of HIV acquisition.

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Integrated Study Dashboard

This dashboard, developed under the BioPIC project, reflects all currently known activities relating to implementation research, modelling, clinical research, and landscaping for new late stage biomedical HIV PrEP options, including lenacapavir for PrEP, cabotegravir, and the dapivirine vaginal ring. To update or add any activities missing from the dashboard, or if you have questions on…

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PrEP Power Demand Generation Toolkit

The PrEP Power demand generation toolkit is intended for use by local partners working with key populations (KP): men who have sex with men, trans and gender diverse people, sex workers, and people who use drugs. The PrEP Power project ran human-centered design (HCD) workshops with community members in Eswatini, Kenya, and Zambia. Everything in…

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PrEP Quiz

The PrEP Quiz was developed to support adolescent girls and young women to explore methods that would align with their lifestyle, needs and personal preferences; and support healthcare providers to provide informed counseling based on client needs. If you are interested in learning more or adapting this tool for use in your setting, please reach…

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LEN Learning Clinic Resources

These interactive learning clinics, hosted by CHAI and Wits RHI, bring together governments, implementing partners, and technical assistance teams to share and discuss early insights from LEN introduction, including practical service delivery innovations and clinical considerations. All resources from learning clinics will be added here as they take place. See the Events page for upcoming…

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LEN Rollout Resources and Tools

The resources listed in this document, alongside insights drawn from the report Getting PrEP Rollout Right This Time, can support countries in the early stages of LEN planning. These tools are being disseminated as part of a coordinated effort between AVAC, CHAI, CIFF, the Global Fund, PEPFAR, PSI, Unitaid, Wits RHI, and WHO under the…

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Nigeria National HIV Prevention Plan 2026–2030

This plan, developed by Nigeria’s Federal Ministry of Health and Social Welfare and National Agency for the Control of AIDS, provides a roadmap for reversing the HIV epidemic in Nigeria.

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Ghana National HIV Prevention Roadmap, 2026-2028

This National HIV Prevention Roadmap 2026-2028 outlines Ghana’s HIV and AIDS prevention measures which are based on the five core prevention pillars -Adolescent Girls and Young Women, Adolescent Boys and Young Men, Vulnerable Populations, Condoms, and Anti-Retroviral based Prevention.

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Implementation Guide for Clinicians on the Delivery of Long-Acting Injectable Pre-Exposure Prophylaxis in Zimbabwe, 2026

These clinical guidelines, developed by Zimbabwe’s Ministry of Health and Child Care in 2026, can be used to support delivery of injectable lenacapavir (LEN) and cabotegravir (CAB).