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Country Overview:
South Africa

Global PrEP Tracker
Last Updated: 8 August 2022

Drug Registration Status

Approved
Not
Approved
Under
Review
Data not
available
Gilead's Truvada (TDF/FTC) Registration
Approved
Generic versions of TDF/FTC for prevention
Approved
Viiv's Apretude (CAB for PrEP) Registration
Under Review
IPM's Dapivirine Ring Registration
Approved
Oral F/TAF (Descovy) Registration
Not Approved

Research, Demonstration and Implementation

Oral PrEP

34 Completed Projects

PrEP Ring

3 Planned/Ongoing Projects

Injectable PrEP

5 Planned/Ongoing Projects

Policy Frameworks

South African Guidelines for the Provision of Pre-exposure Prophylaxis (PrEP) to Persons at Substantial Risk of HIV Infection (2020)

National Strategic Plan for HIV, TB and STIs 2017-2022

National Sex Worker HIV Plan (2016-2019)

National Policy on HIV PrEP and Test and Treat (2016)

Est. Cumulative
Initiations:

Total PrEP: 530,378

Oral PrEP: 530,378

PrEP Ring: N/A

Injectable PrEP: N/A

PEPFAR Targets in
COP 2022:

Total PrEP: 224,905

Oral PrEP: N/A

PrEP Ring: N/A

Injectable PrEP: N/A

Featured Resources

Document

South Africa’s COP 2021

The goal of South Africa’s 2021 Country Operational Plan is to maintain progress from 2020 in key areas related to health promotion such as refining efforts to eliminate policy barriers, insitutionalizing client- centered services, helping the country achieve 95-95-95, and spotlighting HIV prevention and treatment access for all populations in need.
Document

Monitoring & Evaluation Plan for the National Strategic Plan on HIV, TB, & STIs, 2017-22

South Africa’s M&E Plan builds on achievements in the fight against HIV/AIDS from the past and continues to lay the groundwork for collecting vital information for this effort into the future. It informs how to improve and scale up service delivery and implementing evidence-based interventions. This Plan also outlines the key indicators, their definitions, data…
Presentation

Breaking the Cycle of Transmission

One of the key questions that this resource answers is why so many HIV prevention interventions are ineffective with adolescent girls and young women (AGYW). Here we outline two locally led project phases that integrate human-centered design methodologies to answer this question and others.
Document

Stakeholder Conversations to Inform Delivery of New HIV Prevention Methods in South Africa

A readout of conversations with local stakeholders about the dapivirine vaginal ring, looking to gain insight on implementation considerations from providers and potential end-users.
Document

Dapivirine Ring Early Introduction Considerations — South Africa Analysis

The OPTIONS Consortium conducted secondary research and interviews with key stakeholders in several countries to understand questions about the ring that could inform demonstration and processes for introducing new biomedical HIV prevention products. South Africa was prioritized for analysis due to the state of the HIV epidemic in the country and experience with ring trials.…
Document

Oral PrEP Youth Dialogues South Africa

The OPTIONS Consortium, in close collaboration with the South African Department of Health, developed the creative concept ‘We Are The Generation That Will End HIV’ and applied it to all information, education and communication (IEC) material. The creative concept aimed to generate demand for oral PrEP as an additional and acceptable HIV prevention method. Short…