The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.
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Journal of Adolescent Health Special Issue: Lessons Learned in Providing PrEP for HIV for Adolescents and Young People at Scale
This special supplement of the Journal of Adolescent Health combines 11 scientific articles and two commentaries highlighting PrEP implementation studies among Brazil and South Africa adolescents and youth. These articles highlight the unique HIV vulnerabilities and PrEP barriers experienced by youth in these countries and the implementation strategies required to address these barriers. Five articles…
Efficacy and Safety of Long-Acting Cabotegravir Compared with Daily Oral Tenofovir Disoproxil Fumarate Plus Emtricitabine to Prevent HIV Infection in Cisgender Men and Transgender Women who Have Sex with Men 1 Year after Study Unblinding: A secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial
This article from The Lancet HIV describes findings from the first unblinded year of the HIV Prevention Trials Network (HPTN) 083 study, which compared safety and efficacy of cabotegravir and tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as HIV prevention for transgender women and men who have sex with men in Argentina, Brazil, Peru, South Africa, Thailand, the…
Efficacy, Safety, Tolerability, and Pharmacokinetics of Long-acting Injectable Cabotegravir for HIV Pre-exposure Prophylaxis in Transgender Women: A secondary analysis of the HPTN 083 trial
This article from the Lancet HIV discusses the results of a secondary analysis of data from the HPTN 083 trial of cabotegravir for PrEP, looking specifically at the cohort of transgender women included in the study.
Important Steps for PrEP Uptake Among Adolescent Men Who Have Sex With Men and Transgender Women in Brazil
This journal article from PLOS ONE analyzed the PrEP uptake process and factors associated with daily oral PrEP initiation among adolescent men who have sex with men and transgender women in Brazil.
Monitoring & Evaluation
Special Issue of the PrEP1519 Brazil Study
Cadernos de Saúde Pública released a special issue of the PrEP1519 study using baseline data. Click here more details. For a full breakdown of the free journal articles, please see below. Combination HIV prevention for adolescent men who have sex with men and adolescent transgender women in Brazil: vulnerabilities, access to healthcare, and expansion of…
Monitoring & Evaluation, Research
Same-day Initiation of Oral Pre-exposure Prophylaxis among Gay, Bisexual, and Other Cisgender Men who Have Sex with Men and Transgender Women in Brazil, Mexico, and Peru (ImPrEP): A prospective, single-arm, open-label, multicentre implementation study
This article from The Lancet HIV assesses the feasibility of same-day oral PrEP delivery amongst gay and bisexual men who have sex with men and transgender women in Brazil, Mexico, and Peru.
Travestis, Transgender Women and Young MSM are at High Risk for PrEP Early Loss to Follow-up in Rio de Janeiro, Brazil
This article from the Brazilian Journal of Infectious Diseases identifies factors associated with PrEP early loss to follow-up among gay, bisexual and other men who have sex with men, travestis, and transgender women in Rio de Janeiro, Brazil.
Monitoring & Evaluation, Service Delivery
Characterizing the Impact of the COVID-19 Pandemic on HIV PrEP care: A review and synthesis of the literature
This review from the journal AIDS and Behavior provides an examination of the influences of the COVID-19 pandemic on engagement in the PrEP care continuum, and looks at the barriers and facilitators to PrEP uptake during this time.
Research, Service Delivery
Transgender Women in HPTN 083: An evaluation of safety, efficacy, and gender affirming hormonal therapy interactions with long-acting cabotegravir
This poster from AIDS 2022 presents an analysis of results from the HPTN 083 study, looking at the impact of feminizing gender affirming hormones on cabotegravir (CAB) for PrEP pharmacokinetics.
Central America & Brazil Region ROP, 2022 (Español)
El objetivo del Plan Operativo Regional 2022 para la región de América Central y Brasil es mantener el progreso desde 2021 en áreas clave relacionadas con la promoción de la salud, como perfeccionar los esfuerzos para eliminar las barreras políticas, institucionalizar los servicios centrados en el cliente, ayudar al país a lograr 95-95 -95, y…