Resource Library

Dapivirine Vaginal Ring for HIV Prevention: Modeling health outcomes, drug resistance and cost‐effectiveness

This paper evaluates the potential epidemiological impact and cost-effectiveness of dapivirine vaginal ring PrEP among 22- to 45-year-old women in KwaZulu-Natal, South Africa.

Financing & Costing, Research

Kenya Dapivirine Ring Rollout Scenarios

As Kenya considers introduction of the dapivirine ring, a new HIV prevention method for women, an outstanding question is how and where the ring should be introduced relative to oral PrEP. To support decision making, the PROMISE Consortium developed this analysis to consider several possible scenarios, defined by HIV incidence among women and adolescent girls…

Research, Service Delivery

Creating demand for the Dapivirine vaginal ring

This presentation outlines lessons learned from ring clinical trials and oral PrEP programs in Kenya, South Africa, Uganda, and Zimbabwe that can be applied to the development of demand creation strategies.

Demand Creation/Marketing

Dapivirine Ring Design Guide: Human-Centered Design Research to Increase Uptake and Use

USAID's Center for Accelerating Innovation and Impact applied a human-centered design approach to better understand how IPM's dapivirine ring and other HIV prevention products could fit into young women's lives. This guide offers design concepts and tools to encourage and increase dapivirine ring uptake and use.

Demand Creation/Marketing

Microbicide Trials Network-043 – B-PROTECTED Study

Microbicide Trials Network-043, or B-PROTECTED, is a Phase IIIb open-label study that evaluated the safety and acceptability of the monthly dapivirine ring and daily oral PrEP in women who are breastfeeding, a time of heightened vulnerability for acquiring HIV.

Research

Use of the Dapivirine vaginal ring and effect on cervical cytology abnormalities

This study aims to determine if the dapivirine vaginal ring and the ring device alone (flexible silicone matrix polymer) was associated with the development of cervical cytology abnormalities.

Research, Service Delivery

Vaginal Ring Acceptability and Related Preferences among Women in Low- and Middle-income Countries: A systematic review and narrative synthesis

The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). This article outlines a systematic review of VR acceptability, values and preferences among women in low- and middle-income countries (LMIC) to inform further investment and/or guidance on VR use for HIV prevention.

Research

HOPE Protocol Team Meeting Lessons Learned from PrEP Rollout for the Dapivirine Ring

This presentation outlines lessons from oral PrEP demonstration projects that could be applied to the rollout of the dapivirine vaginal ring as well as plans for ring introduction.

Research

The Years Ahead in Biomedical HIV Prevention Research

This graphic shows the updated status of large-scale prevention trials through 2024.

Community/Advocacy