Resource Library

4 August 2022

Eswatini PrEP Ring Stakeholder Consultations Summary

This country-level analysis from Eswatini shares key stakeholder perceptions of the ring and is the product of consultations led by WHO, IPM, and MOSAIC during the period December 2021 – March 2022.

Community/Advocacy

2 August 2022

Dapivirine Ring: Messaging and Positioning in Eswatini

During 2021-2022, The Busara Centre for Behavioral Economics carried out market research on communication strategies for the PrEP ring in Eswatini in partnership with IPM and FHI 360. The resulting report describes 12 recommended communication strategies for positioning the PrEP ring in Eswatini, along with a description of the context in Eswatini and population segments…

Demand Creation/Marketing

21 July 2022

Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study

The Ring Study, a phase 3 trial, showed a favourable safety profile and a 31% HIV infection risk reduction for a vaginal ring containing 25 mg of dapivirine, compared with a placebo ring. This article outlines the DREAM study, which aimed to evaluate safety, adherence, and HIV incidence in those using the dapivirine vaginal ring…

Research

Dapivirine Vaginal Ring for HIV Prevention: Modeling health outcomes, drug resistance and cost‐effectiveness

This paper evaluates the potential epidemiological impact and cost-effectiveness of dapivirine vaginal ring PrEP among 22- to 45-year-old women in KwaZulu-Natal, South Africa.

Financing & Costing, Research

Kenya Dapivirine Ring Rollout Scenarios

As Kenya considers introduction of the dapivirine ring, a new HIV prevention method for women, an outstanding question is how and where the ring should be introduced relative to oral PrEP. To support decision making, the PROMISE Consortium developed this analysis to consider several possible scenarios, defined by HIV incidence among women and adolescent girls…

Research, Service Delivery

Creating demand for the Dapivirine vaginal ring

This presentation outlines lessons learned from ring clinical trials and oral PrEP programs in Kenya, South Africa, Uganda, and Zimbabwe that can be applied to the development of demand creation strategies.

Demand Creation/Marketing

Dapivirine Ring Design Guide: Human-Centered Design Research to Increase Uptake and Use

USAID's Center for Accelerating Innovation and Impact applied a human-centered design approach to better understand how IPM's dapivirine ring and other HIV prevention products could fit into young women's lives. This guide offers design concepts and tools to encourage and increase dapivirine ring uptake and use.

Demand Creation/Marketing

Microbicide Trials Network-043 – B-PROTECTED Study

Microbicide Trials Network-043, or B-PROTECTED, is a Phase IIIb open-label study that evaluated the safety and acceptability of the monthly dapivirine ring and daily oral PrEP in women who are breastfeeding, a time of heightened vulnerability for acquiring HIV.

Research

Use of the Dapivirine vaginal ring and effect on cervical cytology abnormalities

This study aims to determine if the dapivirine vaginal ring and the ring device alone (flexible silicone matrix polymer) was associated with the development of cervical cytology abnormalities.

Research, Service Delivery