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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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10 February 2023

Coordinating Implementation Science for CAB for PrEP: Focus on Research and Surveillance during Pregnancy and Breastfeeding

These notes outline the key takeaways of a Think Tank focussing on CAB for PrEP implementation research and surveillance during pregnancy and breastfeeding. The Think Tank was part of an ongoing series by BioPIC and the WHO on coordinating implementation science for injectable CAB for PrEP.

Monitoring & Evaluation, Research

Document
7 February 2023

RISE CAB for PrEP Training Toolkit

With the release of the WHO Guidelines on Long-Acting Injectable Cabotegravir for HIV Prevention in 2022, HIV prevention programs and implementing partners are working to prepare for rapid expansion of additional methods of HIV pre-exposure prophylaxis (PrEP). Experience from the scale-up of previous HIV prevention programs demonstrates the advantages of ready-made provider capacity building resources…

Service Delivery

External Link
6 February 2023

Optimizing Uptake of Long-Acting Injectable Pre-exposure Prophylaxis for HIV Prevention for Men Who Have Sex with Men

This article from AIDS and Behavior describes the results of a discrete choice experiment on preferences for oral or injectable PrEP amongst gay, bisexual, and other men who have sex with men in the USA, including mode of administration, side-effects, monetary cost, and time cost.

Research

External Link
30 January 2023

An Update on Expanding HIV Preexposure Prophylaxis

This article from the Journal of the American Academy of Physicians Assistants describes how to better employ PrEP in the United States in light of changes to the Centers for Disease Control guidelines on PrEP counselling, monitoring, and delivery, and approval of injectable cabotegravir for PrEP by the US Food and Drug Administration.

Monitoring & Evaluation, Normative Guidance/Policies, Service Delivery

External Link
23 January 2023

Estimating the Impact of HIV PrEP Regimens Containing Long-acting Injectable Cabotegravir or Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine among Men who Have Sex with Men in the United States: A mathematical modelling study for HPTN 083

This article from The Lancet Regional Health- Americas describes the results of a modelling exercise which compares the potential population-level impact of oral PrEP (TDF/FTC) and Cabotegravir for PrEP among gay and bisexual men who have sex with men in Atlanta, Georgia, USA.

Research

External Link
16 January 2023

The Potential of Long-Acting, Injectable PrEP, and Impediments to its Uptake

This article from the Journal of Urban Health outlines potential advantages and barriers to uptake of cabotegravir for PrEP.

Service Delivery

External Link
16 January 2023

Predicted Effects of the Introduction of Long-acting Injectable Cabotegravir Pre-exposure Prophylaxis in Sub-Saharan Africa: A modelling study

This article from The Lancet HIV uses modelling to project the health benefits and risks of cabotegravir for PrEP introduction in settings in sub-Saharan Africa.

Research

External Link
3 January 2023

MOSAIC Gender and Youth Strategy

This Gender and Youth Strategy, developed by the MOSAIC consortium, offers an analysis of the gender- and age-related barriers faced by — and the opportunities that could be leveraged in collaboration with — potential users of PrEP.

Community/Advocacy, Demand Creation/Marketing, Service Delivery

Document
23 December 2022

Costs and Cost-Effectiveness of Biomedical, Non-Surgical HIV Prevention Interventions: A systematic literature review

This article from PharmacoEconomics synthesizes findings on cost and cost-effectivness of different biomedical HIV prevention options and identifies remaining knowledge gaps to suggest future research priorities.

Financing & Costing, Research

External Link
22 December 2022

Long-acting HIV Pre-exposure Prophylaxis (PrEP) Approaches: Recent advances, emerging technologies, and development challenges

This review from Expert Opinion on Drug Delivery discusses the current state of the long acting PrEP field, recent advances, and emerging technologies, including ARV prodrug modifications and new drug delivery systems. Technological challenges, knowledge gaps, preclinical testing considerations, and future directions important in the context of clinical translation and implementation of long acting HIV…

Research

External Link