Resource Library

PROMISE Project Brief

The USAID funded PROMISE program supports early product introduction planning for the monthly dapivirine ring in sub-Saharan Africa, with the goal of shaping the market and establishing a service delivery platform to support future multipurpose and longer-acting vaginal rings.

Listening to Young Women in Kenya and South Africa to Inform Multipurpose “2-in-1” Products for HIV and Pregnancy Prevention

The Tablets, Ring, Injections as Options study, or TRIO, was conducted with young women aged 18 to 30 in Kisumu, Kenya and Soshanguve, South Africa between 2015 and 2017. The study examined young women's perspectives on future MPT in a clinical study of three placebo MPT products.

Research

What End-Users Think About HIV Prevention Products and Multipurpose Prevention Technologies (MPTs)

The Tablets, Ring, Injections as Options study, or TRIO, was conducted with young women aged 18 to 30 in Kisumu, Kenya and Soshanguve, South Africa between 2015 and 2017. The study examined young women's perspectives on future MPT in a clinical study of three placebo MPT products. TRIO identified anticipated enablers and barriers to adoption…

Research

Dapivirine Ring Compendium of End-User Insights

A summary of existing end-user research findings related to the ring and gaps remaining, all in a digestible compendium.

Research

Measuring Social Harms in Research and Programs on Women-Initiated HIV Prevention Methods

This brief summarizes how five HIV prevention trials defined and measured social harms and makes recommendations for future research and programs.

Monitoring & Evaluation, Research

Private and Public Introduction Stakeholder Consultations

This slide deck shares key stakeholder insights on potential introduction pathways and related considerations for the ring via both the private and public sector in Kenya, South Africa and Zimbabwe. This tool is intended to be used by implementers and researchers as they consider how to incorporate the dapivirine vaginal ring into existing and future…

Service Delivery

Market Authorization 101

This slide deck outlines a potential path of market authorization for the dapivirine vaginal ring. It clarifies the necessary regulatory, normative guidance, and policy steps at the global and country levels that would be needed to support ring introduction. This Market Authorization 101 deck is intended to illustrate the ring pathway to market and assist…

Normative Guidance/Policies

What Have We Learned About Adolescent Girls and Young Women and HIV Prevention?

Using survey data collected from ongoing, planned and completed projects studying HIV prevention for adolescent girls and young women, it is possible to identify trends and gaps in the data, and provide a clear snapshot of what we know now.

Research

The Dapivirine Ring: Key learnings from like-product introductions

Vaginal insertion and partial efficacy are two challenges that could affect the uptake and continued use of the dapivirine ring. Analyses of the introductions of other products that share similar characteristics provide useful lessons to inform planning for rollout of the dapivirine ring. This paper provides information for planners, implementers, funders, researchers, trainers, providers of…

Research

Social Harms and Use of the Dapivirine Vaginal Ring

The dapivirine ring and other woman-initiated HIV prevention methods are designed to enable women to have more control over their sexual health and risk of HIV exposure, but research has revealed that women's male partners often influence their ability to use these methods. This brief summarizes an analysis of MTN-020/ASPIRE trial data, which showed that…

Research