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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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5 December 2022

A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial of Radiopaque Islatravir-Eluting Subdermal Implants for Pre-exposure Prophylaxis Against HIV-1 Infection

This article from JAIDS describes the results of a randomized, double-blind, placebo-controlled, phase 1 trial of a next-generation radiopaque islatravir-eluting implant to assess safety, tolerability, and pharmacokinetics.

Research

External Link
5 December 2022

PrEP Among Pregnant and Lactating People in 18 PEPFAR-Supported Countries: A review of HIV strategies and guidelines

This article from Global Health: Science and Practice examines the evolution of strategies and guidance on PrEP services for pregnant and lactating people from 18 countries supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR).

Normative Guidance/Policies, Research

External Link
30 November 2022

Approaches to Accelerating the Study of New Antiretrovirals in Pregnancy

This article from the Journal of the International AIDS Society proposes principles and a framework to enhance and accelerate the study of new antiretrovirals in pregnancy, both for treatment and prevention.

Research

External Link
24 November 2022

Potential of Long-Acting Products to Transform the Treatment and Prevention of Human Immunodeficiency Virus (HIV) in Infants, Children, and Adolescents

This article from Clinical Infectious Diseases examines the potential of injectable PrEP for HIV prevention in infants, children, and adolescents.

Research, Service Delivery

External Link
24 November 2022

Barriers to Uptake of Long-Acting Antiretroviral Products for Treatment and Prevention of HIV in Low- and Middle-Income Countries

This article from Clinical Infectious Diseases examines potential barriers to scale-up of injectable PrEP in low and middle income countries.

Research, Service Delivery

External Link
22 November 2022

Mapping Implementation Science with Expert Recommendations for Implementing Change (MIS-ERIC): Strategies to Improve PrEP Use among Black Cisgender Women Living in Mississippi

This article from the Journal of Racial and Ethnic Health Disparities describes an analysis of qualitative interviews undertaken in Mississippi, USA with Black, cisgender women at risk for HIV and community healthcare clinic staff who work directly with this population in order to identify barriers to PrEP uptake and select appropriate implementation strategies to increase…

Demand Creation/Marketing, Research, Service Delivery

External Link
18 November 2022

Uptake of and Adherence to Oral Pre-exposure Prophylaxis among Adolescent Girls and Young Women at High Risk of HIV-Infection in Kampala, Uganda: A qualitative study of experiences, facilitators and barriers

This article from BMC Women’s Health describes the results of a qualitative study exploring the experiences, facilitators and barriers of PrEP uptake and adherence to PrEP among adolescent girls and young women in Kampala, Uganda.

Research, Service Delivery

External Link
18 November 2022

Self-reported and Pill Count Measures of Adherence to Oral HIV PrEP among Female Sex Workers Living in South-Western Uganda

This article from PLOS One reports on a study evaluating PrEP adherence amongst female sex workers in southwestern Uganda using clinic-based pill counts and self-reported measures, and examines factors associated with protective levels of adherence.

Research, Service Delivery

External Link
18 November 2022

Transgender Women in HPTN 083: An evaluation of safety, efficacy, and gender affirming hormonal therapy interactions with long-acting cabotegravir

This poster from AIDS 2022 presents an analysis of results from the HPTN 083 study, looking at the impact of feminizing gender affirming hormones on cabotegravir (CAB) for PrEP pharmacokinetics.

Research

Document
17 November 2022

Initial Implementation of HIV PrEP for People who are Incarcerated in Zambia: A cross-sectional observational study

This article from The Lancet HIV describes a cross-sectional observational study of a PrEP programme implemented between October 2020 and March 2021 in 16 criminal justice facilities in four Zambian provinces.

Research, Service Delivery

External Link