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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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3 October 2025

Lenacapavir Provider Tools and Job Aids

These editable tools, developed by Wits RHI, can be used to support providers delivering lenacapavir (LEN) for PrEP. The downloadable zip file includes: LEN Factsheet for Clients LEN Counselling Job Aid for Clinicians LEN Counselling Job Aid for Counsellors LEN Initiation Algorithm LEN Injection Procedure Chart HIV Prevention Product Comparison Table LEN Stopping and Switching…

Service Delivery

Document
30 September 2025

Dynamic Choice HIV Prevention with Long-acting Injectable Cabotegravir Pre-exposure Prophylaxis in East, Central, Southern, and West Africa: A cost-effectiveness modelling analysis

In randomised controlled trials in Kenya and Uganda, a dynamic choice HIV prevention intervention that offered structured choice of biomedical prevention product and opportunity to change products over time substantially improved prevention coverage; incident HIV infections were eliminated when long-acting cabotegravir was included as an option. This article from The Lancet HIV aims to assess…

Financing & Costing, Research, Service Delivery

External Link
25 September 2025

Prepped to Serve: The Community Pharmacy’s HIV Prevention Toolkit

The Prepped to Serve Toolkit provides a practical roadmap for building capacity, developing partnerships, strengthening workflows, and creating stigma-free, patient-centered pharmacy environments to deliver HIV prevention services in the community.

Service Delivery

External Link
25 September 2025

Empowering Women’s PrEP Choices: Qualitative Insights into Long-Acting PrEP Preferences and Decision-Making during Pregnancy and Breastfeeding in South Africa and Botswana

This article from AIDS and Behavior explores preferences for various long-acting PrEP modalities amongst pregnant and lactating people in Botswana and South Africa. It further examines participants’ HIV risk perception during pregnancy and breastfeeding, their perceived individual-level facilitators and barriers of each PrEP modality, and the support needed by participants for PrEP uptake and continuation.

Research, Service Delivery

External Link
9 September 2025

From Oral PrEP to LEN: Leveling Up Prevention with the WHO–Jhpiego PrEP Provider Training Toolkit

Recording / Slides This 90-minute webinar, presented by Jhpiego and WHO, is intended for communities, providers, policy makers and advocates interested in pre-exposure prophylaxis (PrEP) for HIV prevention. The presenters will provide an overview of the recently launched WHO and Jhpiego Provider Training Toolkit on Use of Oral and Long-Acting HIV PrEP with case-based scenarios…

Service Delivery

Event
5 September 2025

HIV Prevention Re-mix: Current tools, new tools, same goal

Join the UNITED! Movement and AVAC to learn more about the future of HIV prevention and what this means for young people. The webinar will cover: Prevention options currently available Long-acting PrEP products, including those currently available, available soon, and in the pipeline An update on the introduction of six month lenacapavir for PrEP Advocacy…

Community/Advocacy, Research, Service Delivery

Event
19 August 2025

Standard Operating Procedure for Injectable Lenacapavir as Pre-exposure Prophylaxis

This document, developed by the South to South Learning Network, provides an adaptable standard operating procedure (SOP) to support the development and adoption of national SOPs that align with World Health Organization recommendations and guidance on injectable lenacapavir for PrEP. Click here for a version of this resource in Word format.

Normative Guidance/Policies, Service Delivery

Document
14 August 2025

Supporting PrEP Access: HIV Self-Testing in Uptake and Scale-Up

Slides / Recording This webinar, co-hosted by WHO and PSI, will explore the use of HIV self-testing for PrEP initiation and continuation.

Service Delivery, Testing

Event
14 August 2025

New WHO Guidance on Lenacapavir for Prevention and HIV Testing for Long-Acting PrEP

This 60-minute webinar is intended for communities, providers, policy makers and advocates for PrEP, HIV prevention and HIV testing. We will provide an overview of the key takeaways and new guidance from newly released Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. This is the first webinar in a…

Normative Guidance/Policies, Service Delivery, Testing

Event
13 August 2025

Will Lenacapavir be a lever or a let-down? Lessons, Resources, and Considerations for Implementation in the United States

Lenacapavir for PrEP has tremendous potential to increase access and engagement in the United States, reaching individuals who have been unable to embrace PrEP in its previous formulations. How can we ensure that our implementation lifts up, rather than lets down, individuals and communities who need this innovation most? What can we learn from past…

Community/Advocacy, Service Delivery

Event