Resource Library

Adoption of guidelines on and use of oral pre-exposure prophylaxis: a global summary and forecasting study

Widespread adoption of WHO PrEP recommendations coincided with a global increase in PrEP use. Although the 2020 global PrEP target will be missed, strong future growth in PrEP use is possible. New PrEP products could expand the PrEP user base, and, with greater expansion of oral PrEP, further adoption of WHO PrEP recommendations, and simplified…

Normative Guidance/Policies, Research, Service Delivery

Health system adaptations and considerations to facilitate optimal oral pre-exposure prophylaxis scale-up in sub-Saharan Africa

Countries in sub-Saharan Africa have progressively scaled up oral PrEP as part of combination HIV prevention. Initial scale-up efforts have generated progress, drawing lessons from existing HIV interventions, such as antiretroviral therapy and biomedical prevention. However, beset by unprepared health systems, scale-up has been slow. This review synthesises literature on essential considerations for PrEP scale-up,…

Normative Guidance/Policies, Research, Service Delivery

Barriers to Provision HIV Biomedical Prevention Services in sub-Saharan Africa

AVAC conducted a desk review of the HIV prevention policy landscape in eight countries in sub-Saharan Africa. This analysis includes: training requirements for provision of PrEP and contraceptives; clinical guidelines; National Strategic Plans for HIV and Sexual and Reproductive Health; implementation strategies; national policies on age of consent and the criminality of same-sex relationships; in-depth…

Normative Guidance/Policies, Research

CHARISMA Mobile: Developing a digital resource for empowerment counseling, community health clinic model for agency in relationships and safer microbicide adherence

CHARISMA is a PEPFAR- and USAID-funded empowerment counseling intervention designed to help women use oral pre-exposure prophylaxis and other antiretroviral-based HIV prevention technologies safely and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. The intervention, designed to be delivered by lay counselors, is being adapted into a…

Research, Service Delivery

6 June 2022

MTN-045

Archived from the MTN website before it was taken down. Primary Objectives To determine heterosexual couples’ preferences for a DPP product to inform product delivery and future product design to maximize uptake and willingness to use among sub-Saharan African heterosexual couples. To assess the level of influence of the male partner on a woman’s preferences…

Research

1 April 2022

Guidelines for PrEP Ring Pilot Implementation Studies

The intent of this document is to provide adaptable guidelines for the design of Dapivirine ring pilot implementation or post-introduction operations studies to help shape national ring guidelines.

Research, Service Delivery

Stakeholder conversations to inform delivery of multiple HIV prevention methods in Kenya

This report highlights findings from stakeholder conversations implemented in Kenya as part of the PROMISE Collaboration to gain input on implementation considerations for the introduction of the PrEP ring alongside oral PrEP and future inclusion of additional prevention methods for women

Research, Service Delivery

AGYW from Kenya and South Africa: The POWER demonstration project

This poster outlines results from the POWER demonstration project, including characterizing young women who initiate PrEP in Kenya and South Africa, determining PrEP persistence and patterns of use, assessing HIV incidence and drug resistance among PrEP seroconverters, and evaluating different PrEP delivery models.

Research, Service Delivery

MyPrEP Decision Support Tool Increases PrEP Persistence in AGYW Attending an Urban Primary Health Care Clinic in South Africa

A poster presented at HIVR4P 2021 explored the effectiveness of digital tools presented at primary care clinics in South Africa at increasing PrEP adherence.

Research

AGYW’s PrEP-user Journey During an Implementation Science Study in South Africa and Kenya

Journal article appearing in PLOS ONE examining adolescent girls and young women's experience with oral PrEP in South Africa and Kenya. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community.

Research