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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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22 December 2022

Long-acting HIV Pre-exposure Prophylaxis (PrEP) Approaches: Recent advances, emerging technologies, and development challenges

This review from Expert Opinion on Drug Delivery discusses the current state of the long acting PrEP field, recent advances, and emerging technologies, including ARV prodrug modifications and new drug delivery systems. Technological challenges, knowledge gaps, preclinical testing considerations, and future directions important in the context of clinical translation and implementation of long acting HIV…

Research

External Link
22 December 2022

HIV Prevention for the Next Decade: Appropriate, person-centred, prioritised, effective, combination prevention

In light of the development of new HIV prevention technologies, this article from PLOS Medicine proposes a new approach to HIV prevention, that emphasises appropriate, person-centred, prioritised, effective, combination HIV prevention within a framework that reduces existing barriers to services and acknowledges heterogeneity, autonomy, and choice.

Community/Advocacy, Monitoring & Evaluation, Research, Service Delivery

External Link
15 November 2022

Results from a Safety Study of the Dapivirine Vaginal Ring and Oral PrEP in Breastfeeding Mother-Infant Pairs

This poster from AIDS 2022 presents results from the MTN-043/B-Protected trial, comparing the safety profile of the dapivirine vaginal ring against oral PrEP use during breastfeeding.

Research

Document
7 October 2022

Dapivirine Ring Value Chain Situation Analysis- Namibia

This value chain situation analysis can support the introduction of the dapivirine ring in Namibia across two dimensions: considering and prioritizing delivery channels for the ring, and identifying critical steps for ring introduction, including opportunities to build on the introduction and scale-up of oral PrEP.

Service Delivery

Document
7 October 2022

Dapivirine Ring Value Chain Situation Analysis- Zimbabwe

This value chain situation analysis can support the introduction of the dapivirine ring in Zimbabwe across two dimensions: considering and prioritizing delivery channels for the ring, and identifying critical steps for ring introduction, including opportunities to build on the introduction and scale-up of oral PrEP.

Service Delivery

Document
7 October 2022

Dapivirine Ring Value Chain Situation Analysis- Kenya

This value chain situation analysis can support the introduction of the dapivirine ring in Kenya across two dimensions: considering and prioritizing delivery channels for the ring, and identifying critical steps for ring introduction, including opportunities to build on the introduction and scale-up of oral PrEP.

Service Delivery

Presentation
27 September 2022

Clinical Practice Guidelines for Providing the PrEP Ring to Pregnant and Breastfeeding People (English)

These clinical guidelines support implementers to provide the PrEP ring to pregnant and breastfeeding people (PBFP). For the full Clinical Guidelines and Training Package for PrEP for PBFP, click here. This document is in English. For the French version, please click here.

Normative Guidance/Policies

Document
15 August 2022

By women, for women: A story of rings, research and resolve

This dynamic photo story from the International Partnership for Microbicides explains how the dapivirine vaginal ring was conceived, and the journey it has taken to becoming an HIV prevention choice for women.

Community/Advocacy, Research

External Link
12 August 2022

Plan 4 Ring Toolkit: Considerations for Monitoring and Evaluation

In the context of the introduction of the dapivirine ring, this document examines the challenges posed by the current PrEP indicators, proposes new indicators for consideration, and describes how the new indicators would be calculated and used. This tool is part of the Plan 4 Ring toolkit, a suite of resources and tools designed to…

Monitoring & Evaluation

Document
12 August 2022

Plan 4 Ring Toolkit: Demand Creation Lesson Learned

This report documents the lessons of dapivirine ring clinical trials and oral PrEP programs to identify promising strategies and approaches to create consumer demand for the ring and other PrEP products. This tool is part of the Plan 4 Ring toolkit, a suite of resources and tools designed to support national planning for the introduction…

Demand Creation/Marketing

Document