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This report is the result of a highly diverse, multi-stakeholder think tank convened by AVAC, as part of the Coalition to Accelerate and Support Prevention Research (CASPR), in collaboration with the PHASES Project, to identify priority advocacy objectives informed by consensus recommendations, and to develop an action plan to help advance the responsible study of HIV prevention in pregnant and lactating populations to provide urgently needed evidence.

The work of the AVAC/PHASES think tank to advance HIV prevention research with pregnant and lactating people was importantly grounded in a trio of conceptual frameworks:

  1. Reproductive Justice
  2. Conceptual shifts articulated in the Pregnancy and HIV/AIDS: Seeking Equitable Study (PHASES) Ethics Guidance
  3. WHO/IMPAACT framework for accelerated inclusion of pregnant women in pre-licensure clinical trials