Listening to Young Women in Kenya and South Africa to Inform Multipurpose “2-in-1” Products for HIV and Pregnancy Prevention
The Tablets, Ring, Injections as Options study, or TRIO, was conducted with young women aged 18 to 30 in Kisumu, Kenya and Soshanguve, South Africa between 2015 and 2017. The study examined young women’s perspectives on future MPT in a clinical study of three placebo MPT products. TRIO identified anticipated enablers and barriers to adoption and use of future MPT, explored preferred product characteristics, and solicited novel product design recommendations. The project’s key findings and conclusions include that, overall, women desire choice and a diversity of products, and many preferred longer-acting products in familiar forms.
Daily Oral PrEP, Event-Driven PrEP, PrEP Ring, and CAB PrEP Template Guidelines (English)
The intent of this document is to provide adaptable guidelines to support the development and adoption of national guidelines that align with World Health Organization (WHO) pre-exposure prophylaxis (PrEP) recommendations and guidance, including those for tenofovir disoproxil fumarate (TDF)-based daily and event-driven oral PrEP, the monthly dapivirine vaginal ring (“PrEP ring” or “the ring”), and…
Quality Improvement Brief
The Quality Improvement Collaborative (QIC) is a component of the CATALYST study that refines and makes context-specific improvements to the enhanced service delivery package to make it scalable for delivering PrEP choice. The QIC’s multi-country design enables rich learning and problem-solving by providing QI faculty, advisors, coaches, and teams from all CATALYST countries opportunities to…
Insights Report: Communicating the PrEP Category to AGYW
PrEP Category Positioning Market Research Validation Insights from Kenya, South Africa, and Zimbabwe This report is a comprehensive look at what was learned through validating the positioning direction. It explains the methodology, outlines country-specific reactions to the positioning direction, and distills key findings that were leveraged to adjust and refine the positioning to honor the…
Communicating the PrEP Category to Adolescent Girls and Young Women
This strategy brief is intended for use by implementers working to generate demand for PrEP among AGYW. Drawing on all learnings throughout the positioning process, the brief provides a narrative explanation of how to communicate the PrEP category to AGYW and includes actionable guidance on how best to develop communication that will get the attention…
How Might We Motivate Uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers
This article from Frontiers in Reproductive Health describes the results of a study to identify barriers and motivators for Dual Prevention Pill (DPP) uptake to inform the development of a DPP demand generation strategy and broader introduction efforts for Multipurpose Prevention Technologies.
Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial
This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.
PrEP Ring Research Summary
This document is an overview of PrEP ring research in East and Southern Africa, including trial overviews and key findings.
Ring 101 Slide Deck
These slides give an overview of the PrEP ring, including basic information about how it’s used, clinical trial results, and user and partner experience.
PrEP Ring Value Chain Situation Analysis – South Africa – 2021
This value chain situation analysis can support the introduction of the dapivirine ring in South Africa across two dimensions: considering and prioritizing delivery channels for the ring, and identifying critical steps for ring introduction, including opportunities to build on the introduction and scale-up of oral PrEP.
Normative Guidance/Policies, Service Delivery, Vertical Transmission
Elimination of vertical transmission of HIV will require expanded access to HIV prevention strategies, such as PrEP, for pregnant and breastfeeding people. Guidance from the World Health Organization (WHO) supports provision of HIV pre-exposure prophylaxis (PrEP) to pregnant and breastfeeding people (PBFP) who are at continuing substantial risk of HIV infection. Evidence has shown that…