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The Dual Prevention Pill Inspiration Guide

12 December 2025

This Dual Prevention Pill (DPP) “inspiration guide,” developed by AVAC, is designed to equip implementers, health practitioners, public health advocates, and community leaders with the proven methods, insights, and creative strategies needed to effectively market and communicate the DPP to relevant audiences.

Topic(s): Demand Creation/Marketing

Product(s): Dual Prevention Pill, Multipurpose Prevention Technologies

Population(s): Adolescent Girls and Young Women, Cisgender Women

Region(s): Sub-Saharan Africa

Format(s): Toolkit

Countries: Kenya, South Africa, Zimbabwe

Source(s): AVAC

Type: Document

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Featured Resources

Document

The Dual Prevention Pill: A catalyst for integrated HIV and family planning services in Zambia: A policy brief

This policy brief, developed by Copper Rose Zambia and AVAC, presents findings from assessments conducted at seven public health facilities, three community hubs, and five pharmacies which reveal readiness and willingness to deliver the Dual Prevention Pill across various service delivery platforms, especially in community settings.
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A Dual Prevention Pill for HIV & Pregnancy Prevention: A pilot study among adolescent girls and young women in Zimbabwe

This article from AIDS and Behavior describes the results of a study examining whether an over-encapsulated dual prevention pill (DPP) combining PrEP + oral contraceptive would be preferred, acceptable, and improve adherence compared to PrEP alone amongst adolescent girls and young women in Zimbabwe.
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2025 State of Self-Care Report: Self-Care in a changing world

This report from the Self-Care Trailblazer Group provides an update on the state of sexual and reproductive health self-care policy, practice, and evidence that can be used as a resource to strengthen self-care implementation and advocacy. It includes a case study on the Dual Prevention Pill, “Community-Centered Perspectives on the Dual Prevention Pill as a…
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“…this could be a noble idea and a game changer.” The Potential of a Dual Prevention Pill for HIV and Pregnancy Prevention among Adolescent Girls and Young Women in Zimbabwe

This article from PLOS Global Public Health describes the opinions of adolescent girls and young women and health care providers in Zimbabwe regarding the dual prevention pill (DPP), combining oral contraceptives with oral PrEP to simultaneously prevent unintended pregnancy and HIV.
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Multipurpose Prevention Technologies for the Prevention of Unintended Pregnancy, HIV, and Other Sexually Transmitted Infections: Regulatory pathways and challenges

This article from Frontiers in Reproductive Health discusses potential regulatory pathways for multipurpose prevention technologies (MPTs).
Document

Frequently Asked Questions about the Dual Prevention Pill

This factsheet provides answers to the most frequently asked questions about the Dual Prevention Pill (DPP), including what it is, who might use it, and how it can be rolled out.
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Developing and Introducing a Dual Prevention Pill- Oral PrEP & oral contraception for HIV and pregnancy prevention

A coalition of partners is developing a novel Dual Prevention Pill (DPP) for prevention of pregnancy and HIV acquisition in high-need countries. In East and Southern Africa — where the DPP is initially planned for introduction — 65 percent of new HIV infections are amongst women aged 15 and over, and 15 percent of women…
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Integrating HIV Prevention with Family Planning Services for Adolescent Girls and Young Women in Uganda: Perspectives of adolescent girls and young women, health care providers, and policymakers

This article from Frontiers in Reproductive Health discusses the results of a study examining various enablers and barriers to the successful integration of HIV prevention into family planning services in the areas of policy, human resources and infrastructure, resource management, service delivery, community involvement, supply chain management, and monitoring and reporting, and provides insights to…
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“Killing Two Birds with One Stone” – A qualitative study on women’s perspectives on the dual prevention pill in Johannesburg, South Africa

This article from BMC Women’s Health describes the results of a study to investigate the acceptability of a dual prevention pill (DPP), combining oral PrEP and a combined oral contraceptive for HIV and pregnancy prevention, among women in Johannesburg, South Africa.
External Link

Harnessing Private Sector Strategies for Family Planning to Deliver the Dual Prevention Pill, the First Multipurpose Prevention Technology with Pre-exposure Prophylaxis, in an Expanding HIV Prevention Landscape

This article from the Journal of the International AIDS Society describes the results of a scoping exercise to evaluate different private sector delivery channels for the Dual Prevention Pill in Kenya, South Africa, and Zimbabwe.