About PrEP

Advocacy starts with information. Learn more about how PrEP works, how to get it and more.


Daily oral PrEP works if you take it. That’s the bottom line about this prevention strategy, rolling out with tenofovir-based drugs in countries and communities worldwide.


Explore this section to learn about:

  • The Basics—Get simple, straightforward information about what PrEP is, why it’s clear it works, and how it’s being used.
  • Evidence and Research—Trials have shown that daily oral PrEP works if taken correctly and consistently. But there’s still a lot to learn about new PrEP agents and how to deliver oral PrEP.
  • Introductory Materials—Recommended basic resources for learning more about PrEP

Want something specific? Visit the AVAC Resource Database, where you may search using assorted parameters and keywords.

News Spotlight

  • FDA Approves Truvada as PrEP for Adolescents at Risk for HIV

    May 15, 2018

    The US Food and Drug Administration has expanded the approval of Truvada as pre-exposure prophylaxis (PrEP) against HIV to include adolescents. Truvada was approved as an HIV prevention method in 2012 but only for individuals age 18 and older. The new approval expands this indication to include adults and adolescents at risk for HIV.

    Read more

  • Early PrEP Uptake in Africa Study Gives Support for Possibility of Wider Acceptance

    May 9, 2018

    New findings show that nearly a fifth of adults whose risk for HIV infection made them eligible for free PrEP started taking the drug within 30 days — according to a study examining the impacts of health interventions across communities in two East African countries. The study’s authors conclude that this provides further evidence that widespread roll out of PrEP to individuals at high risks for infection across resource-limited communities is feasible.

    Read more