About PrEP

Advocacy starts with information. Learn more about the evidence that shows PrEP works.

Pre-exposure prophylaxis, or PrEP, is a way to help HIV-negative people protect themselves from getting HIV. PrEP involves the use of antiretroviral drugs to reduce the risk of becoming infected with HIV. Although oral PrEP is the only PrEP option currently approved for HIV prevention, other forms of ARV-based primary prevention, including the dapivirine vaginal ring and long-acting injectable cabotegravir are on the horizon as possible additions to the PrEP toolbox.

The Basics

Get simple, straightforward information about what PrEP is and how it works.

About Oral PrEP

Learn more about oral PrEP, the first ARV-based biomedical prevention method approved for HIV prevention.

Evidence and Research for Oral PrEP

PrEP research spans implementation research on delivering PrEP and clinical trials of new options. Learn more about the research and data behind the approvals, findings from national introduction and scale-up, and what products might be next.

About the Dapivirine Vaginal Ring

Learn more about the Dapivirine Ring, an intravaginal silicone ring used for HIV prevention.

Evidence and Research for the Dapivirine Ring

Efficacy data shows that the ring reduces HIV risk by 35 percent, with recent data from open label studies showing greater reduction in HIV risk – 50 percent or more with consistent use of the ring.

About Cabotegravir (CAB-LA)

Learn more about CAB-LA, or long-acting injectable cabotegravir, an antiretroviral drug formulated to be administered once every two months as an injectable form of PrEP.

Evidence and Research for Cabotegravir (CAB-LA)

Data from two studies showed CAB-LA to be effective, safe, and well-tolerated in cisgender MSM, TGW, as well as cisgender women.

PrEPWatch Resource Database

Want something specific? Visit the PrEPWatch Resource Database where you can search using assorted parameters and keywords.