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Oral PrEP uses antiretroviral drugs in pill form to prevent HIV. Today, there are two forms of approved oral PrEP: a combination of tenofovir and emtricitabine or TDF/FTC (brand name Truvada) and a combination of tenofovir, alafenamide and emtricitabine or F/TAF (brand name Descovy). Both are prescribed as daily pills.

Click on their dedicated pages below for more information on each including clinical trial evidence, findings from national scale-up and associated advocacy.

Other forms of oral PrEP are in development and future products may be longer acting or incorporated in multi-purpose technologies that combine HIV prevention with contraception or prevention of other diseases or sexually transmitted infections.

Learn more about PrEP in development: