HIV Prevention Plus Plus: Developing Options that Meet the Full Range of our Sexual and Reproductive Health Needs

Tuesday25April

Virtual

Despite a dynamic research and development (R&D) pipeline for prevention products, male and female condoms remain the only multi-purpose prevention technologies (MPTs) currently available. Yet MPTs are an integral part of the HIV prevention advocacy agenda. For decades, advocates have pushed for products to be developed that simultaneously prevent HIV, other sexually transmitted infections (STIs) and/or pregnancy.

With a growing number of PrEP options already, what will it take to bring a new MPT to market? A Dual Prevention Pill (DPP – https://www.prepwatch.org/products/dual-prevention-pill/) that prevents both HIV and pregnancy could be just two years away. Looking further upstream, there are over 25 other MPTs in the pipeline (https://www.prepwatch.org/research-pipeline/), including vaginal rings, which would follow in the footsteps of the dapivirine vaginal ring recommended by WHO and recently approved in several countries.

Within this fast-evolving HIV prevention landscape, work is already underway to build a platform to introduce the DPP, which could speed up the rollout of other MPTs. Join us to hear what we’ve learned so far on R&D, marketing, counseling and delivery for MPTs – and to discuss what we can do now to prepare prevention markets to include new MPT options.

Featured Speakers: Ruth Akulu, ICWEA and AVAC fellow, Gregorio Millet, amfAR, Dr. Thesla Palanee-Phillips, Wits RHI

Recording / Slides / Resources

This webinar is a part of The Choice Agenda.

Featured Resources

External Link

How Might We Motivate Uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers

This article from Frontiers in Reproductive Health describes the results of a study to identify barriers and motivators for Dual Prevention Pill (DPP) uptake to inform the development of a DPP demand generation strategy and broader introduction efforts for Multipurpose Prevention Technologies.

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Rapid Landscape Analysis of National Vertical Transmission Policies for Inclusion of PrEP for Pregnant and Breastfeeding People

Elimination of vertical transmission of HIV will require expanded access to HIV prevention strategies, such as PrEP, for pregnant and breastfeeding people. Guidance from the World Health Organization (WHO) supports provision of HIV pre-exposure prophylaxis (PrEP) to pregnant and breastfeeding people (PBFP) who are at continuing substantial risk of HIV infection. Evidence has shown that…

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Shaping and Strengthening Markets for a New Era of Choice-based HIV/SRH Programming: Lessons from HIV & FP product introduction Report

This report was from the BioPIC Think Tank, Shaping and Strengthening Markets for a New Era of Choice-based HIV/SRH Programming: Lessons from HIV & FP product introduction. As new HIV prevention products move closer to entering the market, there is an opportunity to design choice-based programs that apply lessons and successes from HIV and FP…

Presentation

Shaping and Strengthening Markets for a New Era of Choice-based HIV/SRH Programming: Lessons from HIV & FP product introduction Slides

These slides were featured at the BioPIC Think Tank, Shaping and Strengthening Markets for a New Era of Choice-based HIV/SRH Programming: Lessons from HIV & FP product introduction. As new HIV prevention products move closer to entering the market, there is an opportunity to design choice-based programs that apply lessons and successes from HIV and…

External Link

Making the Case for Joint Decision-Making in Future Multipurpose Prevention Technology (MPT) Choice: Qualitative findings on MPT attribute preferences from the CUPID study (MTN-045)

This article from the Journal of the International AIDS Society uses data from the Microbicide Trials Network 045 study in Uganda and Zimbabwe to examine (1) how couples make decisions on existing non-Multipurpose Technology (MPT) HIV and pregnancy prevention products; (2) how couples make decisions on future ideal-MPT products; and (3) how these decision-making processes…

External Link

Results of 90 Day Tenofovir plus Levonorgestrel Vaginal Ring Trial: The CONRAD 138 study

This article from PLOS One presents the results of a randomized, placebo controlled phase I trial of the safety, pharmacokinetics, pharmacodynamics, and acceptability of a 90 day tenofovir plus levonorgestrel vaginal ring used continuously or cyclically in women to prevent both pregnancy and HIV.

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DPP Audience & Provider Insights for the DPP Research and Marketing Plan: Phase 1 Research Findings

This report, by M&C Saatchi World Services, AVAC, and partners, highlights learnings from Human-Centered Design Research undertaken in 2022 to understand the values and motivations of potential users and influencers of the Dual Prevention Pill (DPP) in Kenya, South Africa, and Zimbabwe.

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Dual Prevention Pill Desk Review Insights

This desk review by M&C Saatchi collates existing data and insights related to uptake and adherence to HIV prevention, contraceptive, and multi-purpose technology pill products; confirms and identifies gaps in the existing knowledge base; and prompts discussions around key learning questions that need to be addressed to develop a robust and effective marketing and demand…

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Review of Effective Marketing and Demand Creation Strategies in HIV Prevention and Family Planning that May Inform Demand-Side Thinking for the Dual Prevention Pill

This scoping review aims to document effective and sustainable demand creation strategies used in HIV prevention and Family Planning interventions, how they may be adapted for the Dual Prevention Pill (DPP), and explores what could be done differently for the DPP.

External Link

The Years Ahead in Biomedical HIV Prevention Research

This graphic shows the updated status of large-scale prevention trials through 2024.