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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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1 March 2021

Dapivirine Vaginal Ring and Oral PrEP: Simultaneous Use Discussion

Slide presentation discussing women choosing to use both the dapivirine vaginal ring at the same time as oral PrEP — reasons for doing so, safety, ideas for future research.

Demand Creation/Marketing, Service Delivery

Document
1 February 2021

MTN-025

Archived from the MTN website before it was taken down. Primary Objectives Characterize the safety profile associated with the open-label use of the dapivirine (25 mg) vaginal matrix ring (VR) in women Characterize adherence to the open-label use of the dapivirine VR (25 mg) in women Study Summary MTN-025, the HIV Open-label Prevention Extension (HOPE)…

Research

1 February 2021

CHOICE PROMISE: Preparing for Ring Opportunities through Market Introduction Support and Knowledge Exchange

Short introduction to PROMISE and CHOICE, consortiums supporting early product introduction planning for the dapivirine vaginal ring in sub-Saharan Africa.

Demand Creation/Marketing

Document
23 June 2020

Listening to Young Women in Kenya and South Africa to Inform Multipurpose “2-in-1” Products for HIV and Pregnancy Prevention

The Tablets, Ring, Injections as Options study, or TRIO, was conducted with young women aged 18 to 30 in Kisumu, Kenya and Soshanguve, South Africa between 2015 and 2017. The study examined young women's perspectives on future MPT in a clinical study of three placebo MPT products.

Research

Document
23 June 2020

What End-Users Think About HIV Prevention Products and Multipurpose Prevention Technologies (MPTs)

The Tablets, Ring, Injections as Options study, or TRIO, was conducted with young women aged 18 to 30 in Kisumu, Kenya and Soshanguve, South Africa between 2015 and 2017. The study examined young women's perspectives on future MPT in a clinical study of three placebo MPT products. TRIO identified anticipated enablers and barriers to adoption…

Research

Document
2 April 2020

Dapivirine Ring Compendium of End-User Insights

A summary of existing end-user research findings related to the ring and gaps remaining, all in a digestible compendium.

Research

Document
26 March 2020

Measuring Social Harms in Research and Programs on Women-Initiated HIV Prevention Methods

This brief summarizes how five HIV prevention trials defined and measured social harms and makes recommendations for future research and programs.

Monitoring & Evaluation, Research

Document
7 January 2020

Private and Public Introduction Stakeholder Consultations

This slide deck shares key stakeholder insights on potential introduction pathways and related considerations for the ring via both the private and public sector in Kenya, South Africa and Zimbabwe. This tool is intended to be used by implementers and researchers as they consider how to incorporate the dapivirine vaginal ring into existing and future…

Service Delivery

Document
7 January 2020

Market Authorization 101

This slide deck outlines a potential path of market authorization for the dapivirine vaginal ring. It clarifies the necessary regulatory, normative guidance, and policy steps at the global and country levels that would be needed to support ring introduction. This Market Authorization 101 deck is intended to illustrate the ring pathway to market and assist…

Normative Guidance/Policies

Document
10 October 2019

The Dapivirine Ring: Key learnings from like-product introductions

Vaginal insertion and partial efficacy are two challenges that could affect the uptake and continued use of the dapivirine ring. Analyses of the introductions of other products that share similar characteristics provide useful lessons to inform planning for rollout of the dapivirine ring. This paper provides information for planners, implementers, funders, researchers, trainers, providers of…

Research

Document