The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.
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Journal of Adolescent Health Special Issue: Lessons Learned in Providing PrEP for HIV for Adolescents and Young People at Scale
This special supplement of the Journal of Adolescent Health combines 11 scientific articles and two commentaries highlighting PrEP implementation studies among Brazil and South Africa adolescents and youth. These articles highlight the unique HIV vulnerabilities and PrEP barriers experienced by youth in these countries and the implementation strategies required to address these barriers. Five articles…
Efficacy and Safety of Long-Acting Cabotegravir Compared with Daily Oral Tenofovir Disoproxil Fumarate Plus Emtricitabine to Prevent HIV Infection in Cisgender Men and Transgender Women who Have Sex with Men 1 Year after Study Unblinding: A secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial
This article from The Lancet HIV describes findings from the first unblinded year of the HIV Prevention Trials Network (HPTN) 083 study, which compared safety and efficacy of cabotegravir and tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as HIV prevention for transgender women and men who have sex with men in Argentina, Brazil, Peru, South Africa, Thailand, the…
How Might We Motivate Uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers
This article from Frontiers in Reproductive Health describes the results of a study to identify barriers and motivators for Dual Prevention Pill (DPP) uptake to inform the development of a DPP demand generation strategy and broader introduction efforts for Multipurpose Prevention Technologies.
Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial
This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.
Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool
This article from Global Health: Science and Practice describes the results of a study to investigate the impact of the Healthy Relationships Tool, part of the CHARISMA Toolkit, on PrEP adherence amongst women in Johannesburg, South Africa.
PrEPare_Morocco: A Successful Community-based PrEP Delivery Demonstration Program for Men who Have Sex with Men and Female Sex Workers in Morocco
This article from AIDS Care describes the first PrEP demonstration project in the Middle East/North Africa region, which aimed to assess the feasibility and acceptability of a community-based PrEP program for female sex workers and gay and bisexual men who have sex with men in Morocco’s highest HIV prevalence cities: Agadir, Marrakech, and Casablanca.
Efficacy, Safety, Tolerability, and Pharmacokinetics of Long-acting Injectable Cabotegravir for HIV Pre-exposure Prophylaxis in Transgender Women: A secondary analysis of the HPTN 083 trial
This article from the Lancet HIV discusses the results of a secondary analysis of data from the HPTN 083 trial of cabotegravir for PrEP, looking specifically at the cohort of transgender women included in the study.
Integrating HIV Preexposure Prophylaxis With Community-Based Syringe Services for Women Who Inject Drugs: Results from the Project SHE demonstration study
This article from Implementation Science describes the results of a demonstration project in Philadelphia, PA, USA to integrate PrEP provision into a syringe services programme for women who inject drugs.
Research, Service Delivery
Changes in Relationships, HIV Risk, and Feelings towards PrEP: Findings from a qualitative explanatory study among participants in the CHARISMA intervention trial
This article from BMC Women’s Health explores women’s experiences with the CHARISMA randomized controlled trial, which tested whether the CHARISMA intervention mitigated relationship-based challenges to PrEP use, such as intimate partner violence, and looks into why the trial showed null results. Click here for more information on CHARISMA.
Research, Service Delivery
Development of a Relationship Counselling Website to Identify and Mitigate Risk of Intimate Partner Violence in the Context of Women’s PrEP Use
This article from PLOS Digital Health discusses the results of beta-testing CHARISMA mobile, a digital resource to support lay counsellors help women access PrEP safely and and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. Click here for more information on CHARISMA.
Research, Service Delivery