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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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26 November 2025

A Dual Prevention Pill for HIV & Pregnancy Prevention: A pilot study among adolescent girls and young women in Zimbabwe

This article from AIDS and Behavior describes the results of a study examining whether an over-encapsulated dual prevention pill (DPP) combining PrEP + oral contraceptive would be preferred, acceptable, and improve adherence compared to PrEP alone amongst adolescent girls and young women in Zimbabwe.

Research

External Link
21 November 2025

Women’s Preferences for Integrating Multi-product Pre-exposure Prophylaxis Delivery Programs within Services for Sexually Transmitted Infections and Reproductive Health Care in Uganda: A discrete choice experiment

This article from Frontiers in Reproductive Health describes the results of a cross-sectional discrete choice experiment to determine the most preferred attributes and levels of multi-product PrEP programs for adolescent girls and young women in Uganda.

Research, Service Delivery

External Link
3 November 2025

Consolidated Guidelines for the Prevention and Treatment of HIV and AIDS in Uganda, 2022

These guidelines, produced in 2022 by the Uganda Ministry of Health, provide guidance on the diagnosis of HIV, the care of people living with HIV, and the use of antiretroviral drugs for treating and preventing HIV infection, including injectable cabotegravir and the dapivirine vaginal ring.

Normative Guidance/Policies

Document
16 October 2025

Preferences for Long-acting Injectable HIV Pre-exposure Prophylaxis Service Delivery among Male and Female Sex Workers in Uganda: A discrete choice experiment

This article from PLOS Global Public Health explores service delivery preferences for injectable cabotegravir among heterosexual male sex workers and female sex workers in Uganda.

Research, Service Delivery

External Link
9 October 2025

The Impact of Cuts in the US President’s Emergency Plan for AIDS Relief Funding for HIV Pre-exposure Prophylaxis in Sub-Saharan Africa: A modelling study

This article from The Lancet HIV estimates the impact of the PEPFAR funding pause for PrEP on HIV infections in sub-Saharan Africa.

Research

External Link
30 September 2025

Prevention with PURPOSE

This presentation, delivered by Dr Linda-Gail Bekker at IAS 2025, provides an overview of PURPOSE 1 and 2 lenacapavir clinical trial results as well as special considerations for administration to different populations and drug-drug interactions.

Research

Presentation
30 September 2025

Dynamic Choice HIV Prevention with Long-acting Injectable Cabotegravir Pre-exposure Prophylaxis in East, Central, Southern, and West Africa: A cost-effectiveness modelling analysis

In randomised controlled trials in Kenya and Uganda, a dynamic choice HIV prevention intervention that offered structured choice of biomedical prevention product and opportunity to change products over time substantially improved prevention coverage; incident HIV infections were eliminated when long-acting cabotegravir was included as an option. This article from The Lancet HIV aims to assess…

Financing & Costing, Research, Service Delivery

External Link
25 September 2025

Empowering Women’s PrEP Choices: Qualitative Insights into Long-Acting PrEP Preferences and Decision-Making during Pregnancy and Breastfeeding in South Africa and Botswana

This article from AIDS and Behavior explores preferences for various long-acting PrEP modalities amongst pregnant and lactating people in Botswana and South Africa. It further examines participants’ HIV risk perception during pregnancy and breastfeeding, their perceived individual-level facilitators and barriers of each PrEP modality, and the support needed by participants for PrEP uptake and continuation.

Research, Service Delivery

External Link
25 September 2025

HIV Country Planning Hub

This platform, hosted by GBGMC in partnership with national civil society groups and technical collaborators, features national HIV prevention and treatment plans developed by and for communities most critical to reaching the last mile of the HIV response. Each plan reflects local priorities and community-led strategies to reach populations most affected by HIV.

Community/Advocacy, Normative Guidance/Policies

External Link
1 September 2025

“…this could be a noble idea and a game changer.” The Potential of a Dual Prevention Pill for HIV and Pregnancy Prevention among Adolescent Girls and Young Women in Zimbabwe

This article from PLOS Global Public Health describes the opinions of adolescent girls and young women and health care providers in Zimbabwe regarding the dual prevention pill (DPP), combining oral contraceptives with oral PrEP to simultaneously prevent unintended pregnancy and HIV.

Research

External Link