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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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14 November 2023

Efficacy and Safety of Long-Acting Cabotegravir Compared with Daily Oral Tenofovir Disoproxil Fumarate Plus Emtricitabine to Prevent HIV Infection in Cisgender Men and Transgender Women who Have Sex with Men 1 Year after Study Unblinding: A secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial

This article from The Lancet HIV describes findings from the first unblinded year of the HIV Prevention Trials Network (HPTN) 083 study, which compared safety and efficacy of cabotegravir and tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as HIV prevention for transgender women and men who have sex with men in Argentina, Brazil, Peru, South Africa, Thailand, the…

Research

External Link
9 November 2023

New Data, New Opportunities: The expanding evidence base for the PrEP ring

Three MTN studies – REACH, DELIVER, and B-PROTECTED – recently published critical new data on PrEP ring use among adolescent girls and young women (AGYW), pregnant individuals, and breastfeeding individuals in Africa. All studies offer compelling evidence that the ring is safe for use among these populations. Moreover, the REACH study is the first to…

Research, Service Delivery

Event
7 November 2023

How Might We Motivate Uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers

This article from Frontiers in Reproductive Health describes the results of a study to identify barriers and motivators for Dual Prevention Pill (DPP) uptake to inform the development of a DPP demand generation strategy and broader introduction efforts for Multipurpose Prevention Technologies.

Research

External Link
6 November 2023

Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial

This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.

Research

External Link
6 November 2023

Pioneering Self-Care Solutions to Drive Access to HIV Prevention and Family Planning

This online session, part of the 2023 Self-Care Learning and Discovery Series, will amplify lessons from five self-care interventions in family planning and HIV prevention — with case studies on DMPA-SC, the Caya Diaphragm, the Dual Prevention Pill, HIV self-testing, and Triggerise, an mHealth platform – to highlight successful self-care strategies applicable across settings and…

Research, Service Delivery

Event
1 November 2023

PrEP Ring Research Summary

This document is an overview of PrEP ring research in East and Southern Africa, including trial overviews and key findings.

Research

Document
1 November 2023

Ring 101 Slide Deck

These slides give an overview of the dapivirine ring, including basic information about how it's used, clinical trial results, user experience, and upcoming studies and products.

Research

Document
20 October 2023

South Africa PrEP Implementation Study Mapping Analysis

This analysis aims to investigate which questions will/will not be addressed by the current slate of ongoing or planned implementation science to inform decisions about investments in additional research (if needed) and provide an understanding of when insights across key questions will become available to help inform the rollout planning for the new PrEP methods…

Research

Document
19 October 2023

Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool

This article from Global Health: Science and Practice describes the results of a study to investigate the impact of the Healthy Relationships Tool, part of the CHARISMA Toolkit, on PrEP adherence amongst women in Johannesburg, South Africa.

Research

External Link
13 October 2023

Coordinating Implementation Science for CAB for PrEP: Inclusion of Key Populations

This document summarises key takeaways from the BioPIC Think Tank focused on strategies to include trans and gender diverse people, gay and bisexual men who have sex with men, sex workers, and people who use and inject drugs in implementation science projects as well as the rollout and scale-up of cabotegravir for PrEP.

Research

Document