Resource Library

Safety and Drug Quantification of the Dapivirine Vaginal Ring and Oral Pre-Exposure Prophylaxis in Breastfeeding Mother–Infant Pairs (MTN-043): A phase 3B, open-label, randomised trial

This article from The Lancet HIV discusses the results of the Microbicide Trials Network (MTN)-043 trial, which assessed the safety of use of the dapivirine vaginal ring during breastfeeding amongst participants in Malawi, South Africa, Uganda, and Zimbabwe.

Research

Practical Approaches and Case-Based Models for Reaching Men and Boys with Integrated HIV Services

This implementation brief from WHO and UNAIDS highlights strategies to reach men with HIV services, including PrEP services, and contains practical examples and lessons learned from real-world implementation and information on how health policies have incorporated men’s health.

Normative Guidance/Policies, Service Delivery

Determinants of Continuation on HIV Pre-exposure Propylaxis among Female Sex Workers at a Referral Hospital in Uganda: A mixed methods study using COM-B model

This article from BMC Public Health describes the results of a study to evaluate PrEP continuation among female sex workers and explore potential determinants of PrEP adherence within a public referral hospital in urban Uganda.

Monitoring & Evaluation, Research, Service Delivery

Barriers to PrEP Use and Adherence among Adolescent Girls and Young Women in Eastern, Southern, and Western Africa: A scoping review

This article from BMC Women’s Health provides an overview of barriers to PrEP use and adherence by adolescent girls and young women across several African countries.

Research, Service Delivery

Characterizing Populations Prioritized for PrEP in 19 African Countries: A review of national guidance

This article from Journal of the International AIDS Society describes the results of a review of PrEP guidelines in 19 African countries to characterize which populations are prioritized for PrEP in Africa.

Research, Service Delivery

Understanding the Drivers of CAB PrEP Uptake and Use among Women in sub-Saharan Africa to Build Demand for New PrEP Methods

This article from Current HIV/AIDS Reports reviews facilitators and barriers to use of injectable cabotegravir (CAB) for PrEP by women in sub-Saharan Africa.

Demand Creation/Marketing, Research, Service Delivery

Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons

This article from the New England Journal of Medicine describes the results of PURPOSE 2, the Phase III clinical trial for injectable lenacapavir for PrEP, carried out amongst gay and bisexual men who have sex with men, trans men, trans women, and gender non binary individuals in Argentina, Brazil, Mexico, Peru, South Africa, Thailand, and…

Research

Pre-Exposure Prophylaxis Implementation Gaps among People Vulnerable to HIV Acquisition: A cross-sectional analysis in two communities in western Kenya, 2021–2023

This article, from Journal of the International AIDS Society, examines PrEP awareness, uptake, and persistence among participants enrolling into an HIV incidence cohort in Kenya.

Research

Implementation Plan for the Introduction of the PrEP Ring and Long-acting Injectable Cabotegravir for HIV Prevention – Eswatini, August 2024

Normative Guidance/Policies

Initiation and Continued Use of Oral Pre-Exposure Prophylaxis among Pregnant and Postpartum Women in South Africa (PrEP-PP): A demonstration cohort study

This article from The Lancet HIV describes the results of a demonstration study in South Africa, PrEP-PP, to integrate oral PrEP provision into public clinics offering antenatal and postnatal care to pregnant and lactating people.

Research, Service Delivery