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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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14 November 2025

BLUPrInt PrEP Program Builder

The BLUPrInt PrEP Program Builder breaks down the process of making PrEP – whether oral or injectable – available in your setting into six manageable and coherent program components. Each program component includes a Step-by-Step Guide that presents key decision points and health equity considerations that are crucial to PrEP program development, a templated Standard…

Demand Creation/Marketing, Service Delivery, Supply Chain Management

External Link
12 November 2025

Getting LEN Rollout Right: Resources and Tools

The resources listed in this document, alongside insights drawn from the report Getting PrEP Rollout Right This Time, can support countries in the early stages of LEN planning. These tools are being disseminated as part of a coordinated effort between AVAC, CHAI, the Global Fund, PEPFAR, Unitaid, Wits RHI, and WHO under the Coalition to…

Community/Advocacy, Demand Creation/Marketing, Financing & Costing, Monitoring & Evaluation, Normative Guidance/Policies, Service Delivery, Supply Chain Management

Document
26 September 2025

Modernising Demand Generation for HIV Prevention

With HIV prevention budgets under increasing pressure, effective and efficient communication is more vital than ever. As prevention options expand from condoms and HIV self-testing to multiple forms of PrEP tailored, impactful demand creation is essential to drive uptake and support informed choice. This session will explore how to generate demand using data-informed strategies, virtual…

Demand Creation/Marketing

Event
21 July 2025

PrEP Implementation: What’s worked and what are we learning

Recording / Slides Pre-exposure prophylaxis (PrEP) has emerged as a critical tool in the global HIV prevention response. Despite its proven efficacy, global uptake of oral PrEP has been slower than anticipated, falling short of UNAIDS’ 2025 targets. However, several countries have successfully scaled up oral PrEP, and in the process learnt significant lessons, many…

Demand Creation/Marketing, Monitoring & Evaluation, Research, Service Delivery, Supply Chain Management

Event
11 June 2025

Lessons from the Field: ​​Getting PrEP Rollout Right This Time

Thirteen years after oral PrEP’s introduction, global uptake remains slow, with just over 9 million initiations—falling short of UNAIDS’ 2025 targets. While HIV infections are declining in some regions, others are experiencing increasing epidemics. Despite challenges, lessons from oral PrEP and CAB rollout have strengthened health systems for scaling up longer-acting PrEP. AVAC undertook a…

Demand Creation/Marketing, Research

Document
8 April 2025

Guidance for Developing a National Male Engagement Strategy for HIV Prevention

This guidance, produced by the South-to-South Learning Network, can help decision-makers at national level, sub-national level, and at programme level to develop a national male engagement strategy for HIV prevention. This guidance is focussed on vulnerable men who are not a member of a key population.

Community/Advocacy, Demand Creation/Marketing, Service Delivery

Document
18 March 2025

A Health Systems Approach to More Effective Decentralised HIV Prevention: Development of Malawi’s Blantyre Prevention Strategy

This article from BMJ Global Health provides background on and shares the experiences of the Blantyre Prevention Strategy (BPS), a health systems-based approach to HIV prevention that directs investments towards embedding essential functions within Blantyre City and District in Malawi. The approach includes developing district-led systems and capabilities in effective disease surveillance and data-driven targeting,…

Demand Creation/Marketing, Research, Service Delivery

External Link
21 January 2025

PrEP Booklet of Frequently Asked Questions (FAQs): A Peer Outreach Worker Tool

This tool was developed to be used by peer outreach workers, peer educators, and other community-based health providers to help provide comprehensive information about pre-exposure prophylaxis (PrEP) to key population peers.

Community/Advocacy, Demand Creation/Marketing

Document
16 December 2024

Understanding the Drivers of CAB PrEP Uptake and Use among Women in sub-Saharan Africa to Build Demand for New PrEP Methods

This article from Current HIV/AIDS Reports reviews facilitators and barriers to use of injectable cabotegravir (CAB) for PrEP by women in sub-Saharan Africa.

Demand Creation/Marketing, Research, Service Delivery

External Link
29 November 2024

HIV Prevention User Journey Tool

The HIV Prevention Journey Tool was developed to support adolescent girls and young women to explore methods that would align with their lifestyle, needs and personal preferences; and support healthcare providers to provide informed counseling based on client needs. The digital tool, which has been optimized for use on mobile devices, can be accessed here.…

Demand Creation/Marketing, Service Delivery

Document