Addressing the Need for a Preexposure Prophylaxis Monitoring and Evaluation Implementation Guide: Experience From Zambia

28 March 2023

The HIV care continuum comprises well-defined steps and indicators. In contrast, indicators along the preexposure prophylaxis (PrEP) cascade are still in the early stages of implementation. Monitoring and evaluation (M&E) of PrEP services is critical to optimizing PrEP uptake and adherence during periods of HIV risk. We provide an overview of global indicators for PrEP, describe the development process and outcomes of Zambia’s 2022 National Pre-Exposure Prophylaxis (PrEP) Program Monitoring & Evaluation Implementation Guide, and discuss the guide’s implications for other countries in sub-Saharan Africa.

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Coordinating Implementation Science for CAB for PrEP: Linking Modellers with the Latest Implementation Science Evidence, March 2024

This document summarises key takeaways from a March 2024 BioPIC Think Tank to ensure modellers and implementation science researchers remain aligned on the latest cabotegravir for PrEP data and evidence.

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Coordinating Implementation Science: Taking Stock of PrEP Evidence

This document summarises key takeaways from the BioPIC Think Tank held in March 2024 to review existing PrEP evidence and evidence gaps to date.

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Equity of PrEP uptake by race, ethnicity, sex and region in the United States in the first decade of PrEP: A population-based analysis

This article from The Lancet Regional Health- Americas describes trends in PrEP uptake during the first ten years of PrEP provision in the United States by race, ethnicity, sex, and region.

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Exploring Attitudes Toward Pre-Exposure Prophylaxis for HIV Prevention Prior to Implementation Among Female Sex Workers in Malaysia: Results from a qualitative study

This article from Patient Preference and Adherence describes the results of a qualitative study with female sex workers in Malaysia to assess the potential need for PrEP in this population and the factors that determine willingness to use oral PrEP.

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Opportunities for Pharmacist-Delivered Injectable PrEP in the USA

These Quick Take briefings from Georgetown University’s O’Neill Institute for National and Global Health Law provide insights on barriers and opportunities for pharmacist-administered injectable PrEP in the USA, including delivery via mobile pharmacies.

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How Men Influence Young Women Taking PrEP: Perspectives from young women, male partners, and male peers in Siaya county, Western Kenya

This article from BMC Women’s Health describes the results of a study exploring the views of young women, male partners, and male peers of young women in Siaya County, Western Kenya, to illustrate how men influence, and can support, young women in using PrEP.

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Questioning Risk Compensation: Pre-exposure prophylaxis (PrEP) and sexually transmitted infections among men who have sex with men, capital region of Denmark, 2019 to 2022

This article from Eurosurveillance describes the results of a study comparing rates for chlamydia, gonorrhoea and syphilis before and after PrEP initiation in gay and bisexual men who have sex with men in Denmark.

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Uptake and Challenges with Daily Oral Pre-exposure Prophylaxis among Men who Have Sex with Men and Transgender Women, Suburban Yangon, Myanmar

This article from International Health describes PrEP uptake and 12 month retention amongst gay and bisexual men who have sex with men and transgender women in Myanmar during the covid-19 pandemic and a political crisis and includes insights into user motivations for uptake and continuation.

PrEP for Pregnant and Breastfeeding People: Advocacy, Policy, and Programmatic Tools

Evidence shows that offering PrEP is a safe and effective HIV prevention strategy for pregnant and breastfeeding people. Guidance from the World Health Organization (WHO) supports provision of PrEP to pregnant and breastfeeding people (PBFP) who are at continuing substantial risk of HIV infection. Evidence has shown that people have an increased need for HIV…

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Private Sector Market Assessment: Eswatini

This market assessment explores the opportunities and barriers to leveraging private sector channels to expand access to new and existing pre-exposure prophylaxis (PrEP) methods, including oral PrEP, the dapivirine vaginal ring (PrEP ring), and long acting cabotegravir (CAB PrEP) in Eswatini.