An Advocates’ Checklist for Lenacapavir for PrEP Introduction

5 June 2026

The Civil Society Caucus of the Coalition to Accelerate Access to Long-Acting HIV PrEP developed a new resource that offers practical guidance to help civil society, advocates and implementers accelerate equitable access to LEN for PrEP. The checklist is designed to support faster, community-centered rollout ahead of broader generic availability in 2027.

Featured Resources

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Long-Acting PrEP for People With High Vulnerability to HIV Acquisition in Brazil: A cost-effectiveness analysis

This article from Journal of the International AIDS Society assesses the potential clinical and economic impact of offering injectable cabotegravir or lenacapavir to gay and bisexual men who have sex with men and transgender women with high vulnerability to HIV acquisition in Brazil and determines the maximum cost at which they would be cost-effective.

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LEN Rollout Resources and Tools

The resources listed in this document, alongside insights drawn from the report Getting PrEP Rollout Right This Time, can support countries in the early stages of LEN planning. These tools are being disseminated as part of a coordinated effort between AVAC, CHAI, CIFF, the Global Fund, PEPFAR, PSI, Unitaid, Wits RHI, and WHO under the…

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Kenya Integrated Guidelines for Prevention, Treatment and Management of HIV, Sexually Transmitted Infections and Viral Hepatitis, 2026

These clinical guidelines, developed by Kenya’s Ministry of Health in 2026, can be used to support delivery of both PrEP and PEP, including newer, long-acting options such as injectable lenacapavir (LEN), cabotegravir (CAB), and the dapivirine vaginal ring (DVR).

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Global PrEP Tracker

Last update: April 2026 Visit data.prepwatch.org for a dynamic map-based tool to explore trends in PrEP use globally, including by country, product, and time period. Comprehensive datasets are available to download by clicking “download data” in the upper righthand corner. For any questions, contact [email protected]. Introduction to the Global PrEP Tracker

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Policy Review Tool for WHO-Aligned HIV Prevention Service Delivery

This tool, developed by Global Back Gay Men Connected (GBGMC), supports national and subnational programme managers, technical advisors and peer review teams in systematically reviewing existing national HIV PrEP guidelines against the WHO 2025 recommendations on lenacapavir (LEN) for HIV prevention. The goal of this tool is to assess whether national guidelines are comprehensive, equitable…

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PrEP Drug Interaction Checker

This website, developed and maintained by the University of Liverpool, provides clear, trustworthy, and up-to-date information about how different PrEP options, including oral PrEP, cabotegravir, lenacapavir, and the dapivirine vaginal ring, can interact with other drugs.

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Zambia PrEP Training Materials for Clinicians and Community Mobilisers

These materials, developed by Zambia’s Ministry of Health, can be used to train clinicians and mobilisers in delivery of PrEP methods, including injectable lenacapavir (LEN), cabotegravir (CAB), the dapivirine vaginal ring (DVR), the Dual Prevention Pill (DPP), and oral PrEP.

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Zambia Guidelines for Pre and Post-Exposure Prophylaxis for HIV Infection, 2025

These clinical guidelines, developed by Zambia’s Ministry of Health in 2025, can be used to support delivery of both PrEP and PEP, including newer, long-acting options such as injectable lenacapavir (LEN), cabotegravir (CAB), and the dapivirine vaginal ring (DVR), as well as the Dual Prevention Pill and oral PrEP.

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HIV Prevention Ambassador Training Package and Toolkit

The HIV Prevention Ambassador Training Package and Toolkit was created to prepare potential and current PrEP users to be leaders – or “Ambassadors” – in the rollout of PrEP for HIV prevention in their communities. Through interactive activities, discussion, and action planning, the training prepares Ambassadors to share information with their peers about PrEP methods…

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Early Experiences with Usage of Long-acting Injectable Cabotegravir among Adults in Rural Ugandan and Kenyan Communities: Qualitative research from the SEARCH “Dynamic Choice HIV Prevention” intervention trials

This article from Journal of the International AIDS Society describes the results of a qualitative study exploring experiences with injectable cabotegravir (CAB for PrEP) among adults participating in the SEARCH Dynamic Choice HIV Prevention (DCP) trial in rural Kenya and Uganda, which evaluated HIV prevention uptake through a structured, person-centred DCP model.