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From Proof-of-Concept to Prevention Phenomenon in Five Years

7 July 2022

This timeline, first appearing in AVAC Report 2014/15: HIV Prevention on the Line, shows PrEP going from proof-of-concept to prevention phenomenon in five years and can be used to anticipate and speed action on the next generation of ARV-based prevention options.

Topic(s): Research

Product(s): Oral PrEP, TDF/xTC

Source(s): AVAC

Type: External Link

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Featured Resources

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Coordinating Implementation Science: Taking Stock of PrEP Evidence

This document summarises key takeaways from the BioPIC Think Tank held in March 2024 to review existing PrEP evidence and evidence gaps to date.
External Link

Equity of PrEP uptake by race, ethnicity, sex and region in the United States in the first decade of PrEP: A population-based analysis

This article from The Lancet Regional Health- Americas describes trends in PrEP uptake during the first ten years of PrEP provision in the United States by race, ethnicity, sex, and region.
External Link

Exploring Attitudes Toward Pre-Exposure Prophylaxis for HIV Prevention Prior to Implementation Among Female Sex Workers in Malaysia: Results from a qualitative study

This article from Patient Preference and Adherence describes the results of a qualitative study with female sex workers in Malaysia to assess the potential need for PrEP in this population and the factors that determine willingness to use oral PrEP.
External Link

How Men Influence Young Women Taking PrEP: Perspectives from young women, male partners, and male peers in Siaya county, Western Kenya

This article from BMC Women’s Health describes the results of a study exploring the views of young women, male partners, and male peers of young women in Siaya County, Western Kenya, to illustrate how men influence, and can support, young women in using PrEP.
External Link

Questioning Risk Compensation: Pre-exposure prophylaxis (PrEP) and sexually transmitted infections among men who have sex with men, capital region of Denmark, 2019 to 2022

This article from Eurosurveillance describes the results of a study comparing rates for chlamydia, gonorrhoea and syphilis before and after PrEP initiation in gay and bisexual men who have sex with men in Denmark.
External Link

Uptake and Challenges with Daily Oral Pre-exposure Prophylaxis among Men who Have Sex with Men and Transgender Women, Suburban Yangon, Myanmar

This article from International Health describes PrEP uptake and 12 month retention amongst gay and bisexual men who have sex with men and transgender women in Myanmar during the covid-19 pandemic and a political crisis and includes insights into user motivations for uptake and continuation.

PrEP for Pregnant and Breastfeeding People: Advocacy, Policy, and Programmatic Tools

Evidence shows that offering PrEP is a safe and effective HIV prevention strategy for pregnant and breastfeeding people. Guidance from the World Health Organization (WHO) supports provision of PrEP to pregnant and breastfeeding people (PBFP) who are at continuing substantial risk of HIV infection. Evidence has shown that people have an increased need for HIV…
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Private Sector Market Assessment: Eswatini

This market assessment explores the opportunities and barriers to leveraging private sector channels to expand access to new and existing pre-exposure prophylaxis (PrEP) methods, including oral PrEP, the dapivirine vaginal ring (PrEP ring), and long acting cabotegravir (CAB PrEP) in Eswatini.
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CATALYST Interim Learnings (May-November 2023)

In this first interim analysis, the MOSAIC team provides key learnings from preparing for the delivery of PrEP choice, a summary of challenges experienced in implementing the enhanced service delivery model and the solutions introduced, programmatic considerations for countries preparing to introduce new PrEP methods, and a list of publicly accessible tools and resources used…
External Link

Estimating the Costs and Perceived Benefits of Oral Pre-exposure Prophylaxis (PrEP) Delivery in Ten Counties of Kenya: A costing and a contingent valuation study

This article from Frontiers in Reproductive Health describes the results of a study to calculate the actual costs of oral PrEP scale-up in ten counties in Kenya, including a comparison of service delivery models across regions. In addition, the study looked at factors that indicate why some individuals place a greater value on PrEP than…