Insights from a decade of experience with oral PrEP programs offer key lessons for developing and delivering HIV prevention products so that they reach those who could most benefit. The Prevention Market Manager project has developed a suite of resources to frame these insights and explore their implications.
It’s vital that the field learns from the strengths and shortcomings of efforts to date. Oral PrEP has been saving lives. But the policies and programs that bring this groundbreaking HIV prevention product to people who face risk from HIV can and must do better—only a fraction of the people who need PrEP are using it.
These issue briefs explore key lessons covering monitoring and evaluation, generating demand, improving delivery, and reframing risk. They provide practical guidance for researchers, implementers, healthcare providers, policy-makers and advocates to improve existing efforts and, as the HIV prevention pipeline is poised to expand with long-acting products, to apply to the next generation of prevention products and programs.
Download the Issue Briefs
- Reframing Risk in the Context of PrEP
- Generating and Sustaining Demand for PrEP
- Simplifying and Improving PrEP Delivery
- Next Generation M&E for Next-Generation PrEP
Full Report Available
Daily Oral PrEP, Event-Driven PrEP, PrEP Ring, and CAB PrEP Template Guidelines (English)
The intent of this document is to provide adaptable guidelines to support the development and adoption of national guidelines that align with World Health Organization (WHO) pre-exposure prophylaxis (PrEP) recommendations and guidance, including those for tenofovir disoproxil fumarate (TDF)-based daily and event-driven oral PrEP, the monthly dapivirine vaginal ring (“PrEP ring” or “the ring”), and…
Quality Improvement Brief
The Quality Improvement Collaborative (QIC) is a component of the CATALYST study that refines and makes context-specific improvements to the enhanced service delivery package to make it scalable for delivering PrEP choice. The QIC’s multi-country design enables rich learning and problem-solving by providing QI faculty, advisors, coaches, and teams from all CATALYST countries opportunities to…
Insights Report: Communicating the PrEP Category to AGYW
PrEP Category Positioning Market Research Validation Insights from Kenya, South Africa, and Zimbabwe This report is a comprehensive look at what was learned through validating the positioning direction. It explains the methodology, outlines country-specific reactions to the positioning direction, and distills key findings that were leveraged to adjust and refine the positioning to honor the…
Communicating the PrEP Category to Adolescent Girls and Young Women
This strategy brief is intended for use by implementers working to generate demand for PrEP among AGYW. Drawing on all learnings throughout the positioning process, the brief provides a narrative explanation of how to communicate the PrEP category to AGYW and includes actionable guidance on how best to develop communication that will get the attention…
PrEP Product Awareness, Preferences, and Past Experiences among Transgender Women and Men Who Have Sex with Men in Asia and Australia: The PrEP APPEAL Study
This report provides an overview of PrEP Product Awareness, Preferences, and Past Experiences among Transgender Women and Men Who Have Sex with Men in Asia and Australia (PrEP APPEAL), a survey study in 16 countries and territories in Asia and Australia. The overall goal of PrEP APPEAL was to identify values and preferences about PrEP,…
Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial
This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.
Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool
This article from Global Health: Science and Practice describes the results of a study to investigate the impact of the Healthy Relationships Tool, part of the CHARISMA Toolkit, on PrEP adherence amongst women in Johannesburg, South Africa.
Oral PrEP Value Chain Situation Analysis – Nigeria – 2020
This document provides a value chain situation analysis of oral PrEP in Nigeria as at June 2020.
PrEPare_Morocco: A Successful Community-based PrEP Delivery Demonstration Program for Men who Have Sex with Men and Female Sex Workers in Morocco
This article from AIDS Care describes the first PrEP demonstration project in the Middle East/North Africa region, which aimed to assess the feasibility and acceptability of a community-based PrEP program for female sex workers and gay and bisexual men who have sex with men in Morocco’s highest HIV prevalence cities: Agadir, Marrakech, and Casablanca.
Integrating HIV Preexposure Prophylaxis With Community-Based Syringe Services for Women Who Inject Drugs: Results from the Project SHE demonstration study
This article from Implementation Science describes the results of a demonstration project in Philadelphia, PA, USA to integrate PrEP provision into a syringe services programme for women who inject drugs.