Oral PrEP Risk Assessment Tools

The World Health Organization (WHO) recommends oral PrEP be offered to anyone facing a substantial risk of HIV infection as part of a program of combination prevention. The guidelines recommend evaluating substantial risk by considering the following: the local epidemiological context, evidence on relevant risk factors for individuals and groups in that context, and individual assessment.

Undertaking this multi-faceted evaluation is challenging, especially given the limited resources available for HIV prevention broadly. But accurate risk identification is critically important to make sure PrEP is provided to those who need it, and to maximize the reduction of population-level HIV.

A variety of risk assessment tools have been used to date by studies and programs providing oral PrEP. The Prevention Market Manager (PMM) has collected a library of these tools from around the globe. PMM has also conducted a comprehensive analysis of these tools with the goal of answering the following questions:

  • What risk assessment tools are used in the delivery of oral PrEP, and how are they used?
  • How do tools and procedures identify those at substantial risk of HIV infection?
  • What do implementers need from risk tools to optimize the delivery of oral PrEP?

Analysis of Tools
This analysis can assist partners and implementers with understanding who is at high-risk of HIV acquisition, how best to reach them, and how to support high-levels of oral PrEP uptake and strong adherence. Click here for a summary of findings or for a detailed spreadsheet of all tools examined in the study.


Risk Assessment Toolkits

Tools for MSM

Tools for AGYW

Tools for Female Sex Workers