PEP needs some pep! Addressing PEP Neglect in HIV Prevention Research, Programming and Uptake

Thursday3November

PEP, post-exposure-prophylaxis, is an HIV prevention intervention marked by both great promise and profound neglect. It is useful in both occupational and non-occupational contexts – yet uptake, especially in non-occupational contexts – is poor in most places on the planet. Our panel will unpack the issues and offer research, policy, and programming ideas to address PEP neglect and realize its potential.

Speakers

Dr. James Ayieko, Kenya Medical Research Institute (KEMRI)
Dr. Julie Fox, Guy’s and St Thomas’ NHS Trust/ Kings College
Dr. Ken Mayer, Fenway Institute/Harvard
Njambi Njuguna, FHI 360/MOSAIC
Ace Robinson, PCAF

This webinar is presented by The Choice Agenda, a global forum for advocacy on the latest in HIV prevention research.

Featured Resources

Presentation

HIV Post-Exposure Prophylaxis (PEP) Training

This resource, produced by the South Africa National Department of Health, is a comprehensive training on post-exposure prophylaxis (PEP) provision for health care providers.

External Link

A Community-based Dynamic Choice Model for HIV Prevention Improves PrEP and PEP Coverage in Rural Uganda and Kenya: A cluster randomized trial

This article from Journal of the International AIDS Society describes the effect of a dynamic choice model for HIV prevention, delivered by community health workers with clinician support, on the use of biomedical prevention (including PrEP and PEP) amongst persons at risk of HIV in rural Kenya and Uganda. This research was undertaken as part…

External Link

The Lancet HIV- Special Issue on PrEP

The December 2023 issue of The Lancet HIV contains numerous articles featuring the latest research and commentaries on PrEP, including oral PrEP, injectable CAB for PrEP, the dapirivine vaginal ring, and PEP.

Document

HIV Prevention User Journey Tool

The HIV Prevention Journey Tool was developed to support adolescent girls and young women to explore methods that would align with their lifestyle, needs and personal preferences; and support healthcare providers to provide informed counseling based on client needs. The digital tool, which has been optimized for use on mobile devices, can be accessed here.…

Document

Linking PEP and PrEP Services: Job Aid for Providers

This job aid for providers in Eswatini supports linking PEP and PrEP services as elements of a comprehensive combination HIV prevention package. It includes information on understanding PEP, providing PrEP to PEP users, and algorithms for assessing PEP initiation and for assessing PrEP use in clients returning after a full course of PEP. It is…

External Link

Feasibility and Preliminary Effectiveness of Integrating HIV Prevention into an Adolescent Empowerment and Livelihood Intervention at Youth Clubs in Rural Uganda

This article from AIDS Care examines the feasibility and preliminary effectiveness of integrating HIV prevention into youth clubs implementing an “empowerment and livelihood for adolescents” intervention in rural Uganda.

Document

Synthesis of Post-Exposure Prophylaxis (PEP) Policies in MOSAIC Countries

This brief summarizes the PEP policy landscape, how to address barriers to policy and implementation, and provides recommendations to increase PEP uptake as part of HIV prevention. While it focuses on countries within the MOSAIC consortium, the findings are broadly applicable for ministries of health, implementing partners, providers, and potential PEP users alike.

External Link

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection — Second edition

In June 2016, WHO released guidelines on the diagnosis of HIV infection, the use of ARVs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral…