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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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29 August 2023

Changes in Relationships, HIV Risk, and Feelings towards PrEP: Findings from a qualitative explanatory study among participants in the CHARISMA intervention trial

This article from BMC Women’s Health explores women’s experiences with the CHARISMA randomized controlled trial, which tested whether the CHARISMA intervention mitigated relationship-based challenges to PrEP use, such as intimate partner violence, and looks into why the trial showed null results. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
21 August 2023

Development of a Relationship Counselling Website to Identify and Mitigate Risk of Intimate Partner Violence in the Context of Women’s PrEP Use

This article from PLOS Digital Health discusses the results of beta-testing CHARISMA mobile, a digital resource to support lay counsellors help women access PrEP safely and and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
21 August 2023

Dual Prevention Pill: Market Preparation and Introduction Strategy

This strategy, updated in August 2023, is intended for donors, governments, implementing partners and civil society to inform priorities and planning for DPP rollout. The strategy describes activities required to build a cohesive body of evidence and recommends an approach to DPP introduction to focus efforts. Where possible, activities will be embedded into existing programs…

Demand Creation/Marketing, Financing & Costing, Normative Guidance/Policies, Research, Supply Chain Management

Document
10 August 2023

Adolescent Girls and Young Women’s Experiences with Disclosing Oral PrEP or Dapivirine Vaginal Ring Use: A multi-country qualitative analysis

This article from AIDS and Behavior explores adolescent girls and young women’s experiences in disclosing use of oral PrEP and the dapivirine vaginal ring in South Africa, Uganda, and Zimbabwe.

Service Delivery

External Link
10 July 2023

Baseline Preferences for Oral Pre-Exposure Prophylaxis (PrEP) or Dapivirine Intravaginal Ring for HIV Prevention Among Adolescent Girls and Young Women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 Study)

This journal article from PLOS ONE explored baseline preferences for oral PrEP or the dapivirine ring for AGYW (adolescent girls and young women) in South Africa, Uganda, and Zimbabwe.

Monitoring & Evaluation

External Link
13 March 2023

PrEP Use and HIV Seroconversion Rates in Adolescent Girls and Young Women from Kenya and South Africa: The POWER demonstration project

This article from the Journal of the International AIDS Society describes the POWER project, a prospective implementation science evaluation of PrEP delivery for adolescent girls and young women in family planning clinics in Kisumu, Kenya and youth and primary healthcare clinics in Cape Town and Johannesburg, South Africa.

Research, Service Delivery

External Link
6 March 2023

What Motivated Men to Start PrEP? A cross-section of men starting PrEP in Buffalo City Municipality, South Africa

This article from BMC Public Health discusses the results of qualitative interviews with cisgender, heterosexual men initiating PrEP in Buffalo City Municipality, South Africa to explore their perceived HIV acquisition risk, prevention needs, and preferences for PrEP initiation.

Demand Creation/Marketing, Research

External Link
27 February 2023

Impact and Cost-effectiveness of the National Scale-up of HIV Pre-exposure Prophylaxis among Female Sex Workers in South Africa: A modelling analysis

This article from the Journal of the International AIDS Society evaluates the impact and cost-effectiveness of South Africa’s national PrEP programme for female sex workers.

Financing & Costing, Research, Service Delivery

External Link
15 February 2023

Incorporating End-users’ Voices into the Development of an Implant for HIV Prevention: A discrete choice experiment in South Africa and Zimbabwe

This article from BMC Women’s Health describes the results of a discrete choice experiment undertaken with adolescent girls and young women in South Africa and Zimbabwe where participants were asked their preferences for a hypothetical HIV prevention implant.

Research

External Link
10 February 2023

PrEPVacc Study

The PrEPVacc trial, taking place in Mozambique, South Africa, Tanzania, and Uganda from 2018 to 2024, combines an evaluation of experimental HIV vaccines and oral PrEP at the same time. The PrEP arm of the trial compares the effectiveness of TDF/FTC (Truvada) with F/TAF (Descovy).

Research

External Link