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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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17 February 2025

Safety and Drug Quantification of the Dapivirine Vaginal Ring and Oral Pre-Exposure Prophylaxis in Breastfeeding Mother–Infant Pairs (MTN-043): A phase 3B, open-label, randomised trial

This article from The Lancet HIV discusses the results of the Microbicide Trials Network (MTN)-043 trial, which assessed the safety of use of the dapivirine vaginal ring during breastfeeding amongst participants in Malawi, South Africa, Uganda, and Zimbabwe.

Research

External Link
28 November 2024

Catalyzing Progress in the Inclusion of Pregnant and Lactating People in HIV Prevention Research

This satellite session from HIVR4P 2024 provided a comprehensive overview of progress on inclusion of pregnant and lactating people (PLP) in HIV prevention research since a Think Tank on PLP inclusion hosted by AVAC and PHASES in 2022, emphasizing strides in advocacy and research.

Community/Advocacy, Research

External Link
4 November 2024

Initiation and Continued Use of Oral Pre-Exposure Prophylaxis among Pregnant and Postpartum Women in South Africa (PrEP-PP): A demonstration cohort study

This article from The Lancet HIV describes the results of a demonstration study in South Africa, PrEP-PP, to integrate oral PrEP provision into public clinics offering antenatal and postnatal care to pregnant and lactating people.

Research, Service Delivery

External Link
2 September 2024

Meta-analysis of Pregnancy Events in Biomedical HIV Prevention Trials in Sub-Saharan Africa: Implications for gender transformative trials

This article from AIDS and Behavior describes the results of a meta-analysis of pregnancy events in biomedical HIV prevention trials in sub-Saharan Africa undertaken to support trialists moving toward more inclusive clinical and implementation studies for pregnant and lactating people.

Research

External Link
19 July 2024

Women’s Preferences for HIV Prevention Service Delivery in Pharmacies during Pregnancy in Western Kenya: A discrete choice experiment

This article from Journal of the International AIDS Society describes the results of a discrete choice experiment to evaluate where and how pregnant and lactating people in western Kenya preferred to access HIV prevention services, including PrEP.

Research, Service Delivery

External Link
8 April 2024

PrEP Ring for Pregnant and Breastfeeding Women: Summary of research findings in eastern and southern Africa

This brief outlines findings from recent studies which have published critical new data on use of the dapivirine vaginal ring (PrEP ring or ring) among pregnant and breastfeeding people in eastern and southern Africa, offering evidence that the PrEP ring is a safe and effective HIV prevention method for a broader population than was initially…

Normative Guidance/Policies

Document
8 April 2024

PrEP Ring Safety Data in Pregnant and Breastfeeding Women

This slide deck presents emerging evidence to support conversations on expanding pre-exposure prophylaxis (PrEP) ring access for pregnant and breastfeeding women (PBFW) in policy and programmatic rollout.

Normative Guidance/Policies, Research

Presentation
8 April 2024

PrEP for Pregnant and Breastfeeding People: Advocacy, Policy, and Programmatic Tools

Evidence shows that offering PrEP is a safe and effective HIV prevention strategy for pregnant and breastfeeding people.

Monitoring & Evaluation, Normative Guidance/Policies, Service Delivery

29 February 2024

Key Considerations for Integration of PrEP for Pregnant and Breastfeeding people into National Prevention of Vertical Transmission Policies

This brief outlines key recommendations for integration of HIV pre-exposure prophylaxis (PrEP) for pregnant and breastfeeding people (PBFP) in national prevention of vertical transmission policies. Countries aiming to update their policies can refer to these considerations to help advance integration of WHO-recommended actions into their nationally endorsed prevention of vertical transmission strategies.

Normative Guidance/Policies

Document
8 January 2024

PrEP Site Implementation and New Product Readiness Assessment Tool

This tool is intended to provide insight into the current state of PrEP services and to identify critical barriers and facilitators to PrEP implementation. Additionally, this tool is designed to inform preparations for new PrEP product introduction (CAB PrEP, PrEP ring, or both) according to national priorities. Findings from readiness assessment visits using this tool…

Monitoring & Evaluation, Normative Guidance/Policies, Service Delivery

Spreadsheet