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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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30 September 2025

Prevention with PURPOSE

This presentation, delivered by Dr Linda-Gail Bekker at IAS 2025, provides an overview of PURPOSE 1 and 2 lenacapavir clinical trial results as well as special considerations for administration to different populations and drug-drug interactions.

Research

Presentation
25 September 2025

HIV Country Planning Hub

This platform, hosted by GBGMC in partnership with national civil society groups and technical collaborators, features national HIV prevention and treatment plans developed by and for communities most critical to reaching the last mile of the HIV response. Each plan reflects local priorities and community-led strategies to reach populations most affected by HIV.

Community/Advocacy, Normative Guidance/Policies

External Link
1 September 2025

Global Forecast of Long-Acting PrEP Need for Key Populations (2025–2030)

Developed by AVAC, Avenir, and Global Black Gay Men Connect, this first-of-its-kind forecast estimates: 11.16 million person-years of PrEP needed annually by 2030 among men who have sex with men, transgender women, female sex workers, and people who inject drugs Uptake scenarios for cabotegravir, lenacapavir, and oral monthly PrEP Forecasts segmented by region, population group,…

Research

External Link
7 August 2025

Town-Hall – Launch of Key Populations Long-Acting PrEP Demand Forecast

See full slide deck here Join Global Black Gay Men Connect for the official launch of the Key Populations (KP) Long-Acting PrEP Demand Forecast, developed by GBGMC and AVAC in collaboration with Avenir Health. This virtual town hall will spotlight the critical findings of the new forecast, which estimates the future need for long-acting PrEP…

Community/Advocacy, Research, Service Delivery

Event
18 July 2025

Long-Acting PrEP Market Assessment for Key Populations: Global access and readiness report (2025)

This market assessment supports countries, donors, implementing partners, and advocates in making informed decisions about the introduction, scale-up, and equitable delivery of long-acting PrEP among key populations and other priority groups.

Research

External Link
18 March 2025

Frozen Out: Impact of the PEPFAR funding freeze on programs for key populations

This report, developed by Global Black Gay Men Connect (GBGMC) and amfAR, analyses the impact of PEPFAR funding freezes on key populations worldwide, and provides recommendations on a way forward. For live tracking of this impact, see GBGMC’s Tracking the Freeze: Real-Time Impact on Key Populations.

Community/Advocacy, Financing & Costing, Research, Service Delivery

External Link
17 February 2025

Awareness, willingness, and uptake of pre-exposure prophylaxis (PrEP) among men who have sex with men in Ghana

This article from BMC Infectious Diseases discusses the results of a study which aimed to generate estimates on PrEP awareness, uptake, and willingness to use among gay and bisexual men who have sex with men in Ghana.

Research

External Link
17 February 2025

Advancing PrEP Access and Uptake Among Gay Men of Color

This advocacy brief, compiled by NMAC, presents the results of a community-led study to uncover barriers and facilitators to PrEP uptake amongst gay and bisexual men of color. The brief also identifies actionable themes and proposes a three-year advocacy agenda to address disparities and improve health outcomes.

Community/Advocacy, Research

External Link
27 January 2025

Practical Approaches and Case-Based Models for Reaching Men and Boys with Integrated HIV Services

This implementation brief from WHO and UNAIDS highlights strategies to reach men with HIV services, including PrEP services, and contains practical examples and lessons learned from real-world implementation and information on how health policies have incorporated men’s health.

Normative Guidance/Policies, Service Delivery

External Link
29 November 2024

Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons

This article from the New England Journal of Medicine describes the results of PURPOSE 2, the Phase III clinical trial for injectable lenacapavir for PrEP, carried out amongst gay and bisexual men who have sex with men, trans men, trans women, and gender non binary individuals in Argentina, Brazil, Mexico, Peru, South Africa, Thailand, and…

Research

External Link