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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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26 September 2024

Health Impact, Budget Impact, and Price Threshold for Cost-effectiveness of Lenacapavir for HIV Pre-exposure Prophylaxis in Eastern and Southern Africa: A modelling analysis

This article from The Lancet HIV describes the use of the EMOD-HIV model to estimate the health and budget impacts and threshold price at which lenacapavir for PrEP could be cost-effective in eastern and southern Africa.

Financing & Costing, Research

External Link
13 September 2024

We Choose: Adolescent girls and young women’s choice for an HIV prevention product in a cross-over randomized clinical trial conducted in South Africa, Uganda, and Zimbabwe

This article from PLOS One describes decision-making and product choice amongst adolescent girls and young women in South Africa, Uganda, and Zimbabwe when given a choice between oral PrEP and the dapivirine vaginal ring as part of the REACH crossover study.

Research

External Link
13 September 2024

“Killing Two Birds with One Stone” – A qualitative study on women’s perspectives on the dual prevention pill in Johannesburg, South Africa

This article from BMC Women’s Health describes the results of a study to investigate the acceptability of a dual prevention pill (DPP), combining oral PrEP and a combined oral contraceptive for HIV and pregnancy prevention, among women in Johannesburg, South Africa.

Research

External Link
13 September 2024

“I was given PrEP, but had no privacy”: Mystery shopper perspectives of PrEP counseling for adolescent girls and young women in Kisumu County, Kenya

This article from PLOS One describes the results of a study using adolescent girls and young women as “mystery shoppers” in Kenya to identify barriers to effective PrEP service provision.

Research, Service Delivery

External Link
13 September 2024

Formalized Peer Referral to HIV Pre-exposure Prophylaxis Supported with Self-testing: A mixed-methods pilot study among young Kenyan women

This article from Frontiers in Public Health describes a pilot study in Kenya using peer providers and HIV self-test kits to link adolescent girls and young women to PrEP services.

Research, Service Delivery, Testing

External Link
2 September 2024

Meta-analysis of Pregnancy Events in Biomedical HIV Prevention Trials in Sub-Saharan Africa: Implications for gender transformative trials

This article from AIDS and Behavior describes the results of a meta-analysis of pregnancy events in biomedical HIV prevention trials in sub-Saharan Africa undertaken to support trialists moving toward more inclusive clinical and implementation studies for pregnant and lactating people.

Research

External Link
2 September 2024

PrEP Method Switching: Will it Yield Greater Coverage of HIV Protection? Applying Lessons Learned from Family Planning to Guide Future Research in the Context of PrEP Choice

This review from Current HIV/AIDS Reports draws parallels between HIV prevention and family planning by summarizing how method choice and product switching affected contraceptive coverage globally, synthesizes what is known about PrEP product switching, and outlines evidence gaps to help guide future research on PrEP switching in the context of choice.

Research

External Link
20 August 2024

The Long Wait for Long-acting HIV Prevention and Treatment Formulations

This commentary from The Lancet HIV calls on WHO, financial donors, manufacturers, and governments to take coordinated action to make long-acting HIV prevention and treatment available at scale in lower and middle income countries.

Community/Advocacy, Research, Service Delivery

Document
16 August 2024

Harnessing Private Sector Strategies for Family Planning to Deliver the Dual Prevention Pill, the First Multipurpose Prevention Technology with Pre-exposure Prophylaxis, in an Expanding HIV Prevention Landscape

This article from the Journal of the International AIDS Society describes the results of a scoping exercise to evaluate different private sector delivery channels for the Dual Prevention Pill in Kenya, South Africa, and Zimbabwe.

Research, Service Delivery

External Link
5 August 2024

Client Experiences with “Dynamic Choice Prevention,” a Model for Flexible Patient-centred HIV Prevention Delivery in Rural Eastern Africa

This article from Journal of the International AIDS Society discusses client experiences of a dynamic choice model for HIV prevention piloted in Kenya and Uganda under the SEARCH study, where clients were supported to select HIV prevention method, testing mode, and service delivery channel from a range of options.

Research, Service Delivery

External Link