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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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10 December 2025

The Dual Prevention Pill: A catalyst for integrated HIV and family planning services in Zambia: A policy brief

This policy brief, developed by Copper Rose Zambia and AVAC, presents findings from assessments conducted at seven public health facilities, three community hubs, and five pharmacies which reveal readiness and willingness to deliver the Dual Prevention Pill across various service delivery platforms, especially in community settings.

Community/Advocacy, Normative Guidance/Policies

Document
8 December 2025

South Africa Lenacapavir Implementation Guidelines, 2025

This guideline, developed by South Africa’s National Department of Health, is intended to provide comprehensive clinical, programmatic, and operational direction for the safe, effective, and equitable rollout of lenacapavir as a long-acting injectable option for HIV PrEP in South Africa.

Normative Guidance/Policies

Document
3 December 2025

Canadian Guideline on HIV Pre- and Post-exposure Prophylaxis: 2025 update

These 2025 guidelines provide an update to Canada’s 2017 PrEP guidelines, and were developed by the Canadian Institutes of Health Research (CIHR) Pan-Canadian Network for HIV/AIDS and STBBI (sexually transmitted and bloodborne infections) Clinical Trials Research.

Normative Guidance/Policies

External Link
24 November 2025

European Standards of HIV Prevention and Care: Module on pre-exposure prophylaxis, 2025

These standards of care for HIV, developed by the European Centre for Disease Prevention and Control (ECDC) in partnership with the European AIDS Clinical Society (EACS) define the expected, or desired, quality of prevention for people at risk of HIV acquisition. The standards are person-centred in their approach with a specific focus on being equitable,…

Normative Guidance/Policies

Document
21 November 2025

Ukraine HIV Clinical Guidelines 2025

These clinical guidelines, released by the Ukraine Ministry of Health in 2025, include the latest recommendations for HIV services, including oral PrEP and injectable cabotegravir (CAB) for PrEP.

Normative Guidance/Policies

Document
7 November 2025

2025 State of Self-Care Report: Self-Care in a changing world

This report from the Self-Care Trailblazer Group provides an update on the state of sexual and reproductive health self-care policy, practice, and evidence that can be used as a resource to strengthen self-care implementation and advocacy. It includes a case study on the Dual Prevention Pill, “Community-Centered Perspectives on the Dual Prevention Pill as a…

Research, Service Delivery

External Link
3 November 2025

Consolidated Guidelines for the Prevention and Treatment of HIV and AIDS in Uganda, 2022

These guidelines, produced in 2022 by the Uganda Ministry of Health, provide guidance on the diagnosis of HIV, the care of people living with HIV, and the use of antiretroviral drugs for treating and preventing HIV infection, including injectable cabotegravir and the dapivirine vaginal ring.

Normative Guidance/Policies

Document
3 November 2025

Malawi Service Delivery Guidelines and Standard Operating Procedures for the Provision of HIV Pre-Exposure Prophylaxis using Oral or Long-acting Injectable Options (2024)

The document, produced by the Malawi Ministry of Health, is a guideline to support funders, implementing partners, district health team leads and service providers in implementing Oral and Long-Acting Injectable PrEP in Malawi.

Normative Guidance/Policies

Document
30 September 2025

What Can Modelling Tell Us about the Scale-up of Lenacapavir for Pre-exposure Prophylaxis?

This brief provides a synthesis of evidence from mathematical modelling, as of June 2025, arising from a meeting of programme managers, civil society representatives, mathematical modellers and international HIV prevention stakeholders convened by the Gates Foundation and the Joint United Nations Programme on HIV/AIDS (UNAIDS). The meeting focused on questions currently being considered by HIV…

Research

External Link
25 September 2025

HIV Country Planning Hub

This platform, hosted by GBGMC in partnership with national civil society groups and technical collaborators, features national HIV prevention and treatment plans developed by and for communities most critical to reaching the last mile of the HIV response. Each plan reflects local priorities and community-led strategies to reach populations most affected by HIV.

Community/Advocacy, Normative Guidance/Policies

External Link