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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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18 July 2025

Expanding Access to a Choice-Based HIV Prevention Market

This special JIAS supplement illustrates current evidence, implementation learnings and challenges associated with the introduction, uptake, and continued use of PrEP within the context of an expanded HIV prevention method-mix.

Research, Service Delivery

External Link
11 June 2025

Lessons from the Field: ​​Getting PrEP Rollout Right This Time

Thirteen years after oral PrEP’s introduction, global uptake remains slow, with just over 9 million initiations—falling short of UNAIDS’ 2025 targets. While HIV infections are declining in some regions, others are experiencing increasing epidemics. Despite challenges, lessons from oral PrEP and CAB rollout have strengthened health systems for scaling up longer-acting PrEP. AVAC undertook a…

Demand Creation/Marketing, Research

Document
5 March 2025

2024 Q4 Global PrEP Tracker

AVAC’s Global PrEP Tracker offers two views on PrEP uptake around the world. Visit data.prepwatch.org for a dynamic map-based tool to explore trends in oral PrEP use globally as countries introduce and scale up PrEP programs. For insights on the full scope of PrEP use around the world, the PrEP Tracker as a spreadsheet offers…

Monitoring & Evaluation

Spreadsheet
3 February 2025

Interest in Injectable and Oral PrEP for HIV Prevention Among Women and Men Who Inject Drugs

This article from Journal of Addiction Medicine examines interests and concerns around use of oral and injectable PrEP amongst people who inject drugs in the United States.

Research

External Link
21 January 2025

PrEP Booklet of Frequently Asked Questions (FAQs): A Peer Outreach Worker Tool

This tool was developed to be used by peer outreach workers, peer educators, and other community-based health providers to help provide comprehensive information about pre-exposure prophylaxis (PrEP) to key population peers.

Community/Advocacy, Demand Creation/Marketing

Document
20 January 2025

Determinants of Continuation on HIV Pre-exposure Propylaxis among Female Sex Workers at a Referral Hospital in Uganda: A mixed methods study using COM-B model

This article from BMC Public Health describes the results of a study to evaluate PrEP continuation among female sex workers and explore potential determinants of PrEP adherence within a public referral hospital in urban Uganda.

Monitoring & Evaluation, Research, Service Delivery

External Link
8 January 2025

Oral PrEP Factsheet

This adaptable factsheet can be used by program implementers to raise awareness about oral pre-exposure prophylaxis (PrEP). It highlights tips for using oral PrEP, side effects, and dosing regimens for different groups of people.

Community/Advocacy, Service Delivery

Document
6 January 2025

PEP Template Guidelines (English)

The intent of this document is to provide adaptable guidelines to support the development and adoption of national guidelines that align with World Health Organization (WHO) post-exposure prophylaxis (PEP) recommendations and guidance. The document includes prompts for national-level consideration during the guideline adaptation process.

Normative Guidance/Policies

Document
13 December 2024

Global Acute HIV Infection Algorithm Job Aids for Providers

This tool can assist providers in assessing acute HIV infection (AHI) in clients using oral PrEP, PrEP ring, and CAB PrEP by offering guidance through three steps: HIV testing, recent exposure to HIV assessment, and AHI assessment. Providers are encouraged to use clinical judgement and defer to national guidance as needed.

Normative Guidance/Policies

Document
4 December 2024

I Am More Than HIV Prevention: Results from the HPTN 091 study with transgender women

HPTN 091, the I Am study, evaluated the impact of a multicomponent HIV prevention strategy to increase the uptake and adherence of pre-exposure prophylaxis (PrEP) among transgender women. The strategy included HIV prevention services, gender-affirming hormone therapy, and peer health navigation. This webinar will feature Dr. Tonia Poteat, Ph.D., Duke University School of Nursing, Division…

Research

Event