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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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16 October 2025

Preferences for Long-acting Injectable HIV Pre-exposure Prophylaxis Service Delivery among Male and Female Sex Workers in Uganda: A discrete choice experiment

This article from PLOS Global Public Health explores service delivery preferences for injectable cabotegravir among heterosexual male sex workers and female sex workers in Uganda.

Research, Service Delivery

External Link
15 October 2025

UNAIDS Monthly HIV Services Tracking Platform

This online visual dashboard from UNAIDS compiles data on people reached by services, including PrEP, from former PEPFAR-partner countries.

Research, Service Delivery

External Link
10 October 2025

Self-care Approach to HIV Prevention

How can self-care transform HIV prevention? Join SSLN on Thursday, October 23, 2025, to explore the future of self-care in HIV prevention programming. This crucial session will equip country champions and stakeholders with the technical knowledge and practical tools needed to lead the way. We will cover the risks and opportunities, outline actionable first steps…

Research, Service Delivery

Event
9 October 2025

JIAS Special Issue: Person-Centred HIV Prevention: Supporting people vulnerable to HIV acquisition through tailored programming, service delivery and prevention products

Person-centred care (PCC) is a healthcare approach that focuses on understanding and respecting clients’ preferences, values and beliefs. This special JIAS supplement synthesises evidence from PCC intervention research conducted across Africa, Asia, the Caribbean and North America for HIV prevention.

Monitoring & Evaluation, Research, Service Delivery

External Link
9 October 2025

The Impact of Cuts in the US President’s Emergency Plan for AIDS Relief Funding for HIV Pre-exposure Prophylaxis in Sub-Saharan Africa: A modelling study

This article from The Lancet HIV estimates the impact of the PEPFAR funding pause for PrEP on HIV infections in sub-Saharan Africa.

Research

External Link
30 September 2025

The New Frontier in HIV Pre-exposure Prophylaxis: Lenacapavir Update

In the ongoing search for new methods to address the HIV epidemic, the development of lenacapavir for HIV prevention is a major step forward. Findings from research studies has shown that twice-yearly injection of long-acting lenacapavir provides protection against HIV infection. This discovery offers great promise in advancing our progress towards ending AIDS as a…

Research

Event
30 September 2025

Prevention with PURPOSE

This presentation, delivered by Dr Linda-Gail Bekker at IAS 2025, provides an overview of PURPOSE 1 and 2 lenacapavir clinical trial results as well as special considerations for administration to different populations and drug-drug interactions.

Research

Presentation
30 September 2025

Dynamic Choice HIV Prevention with Long-acting Injectable Cabotegravir Pre-exposure Prophylaxis in East, Central, Southern, and West Africa: A cost-effectiveness modelling analysis

In randomised controlled trials in Kenya and Uganda, a dynamic choice HIV prevention intervention that offered structured choice of biomedical prevention product and opportunity to change products over time substantially improved prevention coverage; incident HIV infections were eliminated when long-acting cabotegravir was included as an option. This article from The Lancet HIV aims to assess…

Financing & Costing, Research, Service Delivery

External Link
30 September 2025

What Can Modelling Tell Us about the Scale-up of Lenacapavir for Pre-exposure Prophylaxis?

This brief provides a synthesis of evidence from mathematical modelling, as of June 2025, arising from a meeting of programme managers, civil society representatives, mathematical modellers and international HIV prevention stakeholders convened by the Gates Foundation and the Joint United Nations Programme on HIV/AIDS (UNAIDS). The meeting focused on questions currently being considered by HIV…

Research

External Link
25 September 2025

Empowering Women’s PrEP Choices: Qualitative Insights into Long-Acting PrEP Preferences and Decision-Making during Pregnancy and Breastfeeding in South Africa and Botswana

This article from AIDS and Behavior explores preferences for various long-acting PrEP modalities amongst pregnant and lactating people in Botswana and South Africa. It further examines participants’ HIV risk perception during pregnancy and breastfeeding, their perceived individual-level facilitators and barriers of each PrEP modality, and the support needed by participants for PrEP uptake and continuation.

Research, Service Delivery

External Link