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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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10 July 2023

Baseline Preferences for Oral Pre-Exposure Prophylaxis (PrEP) or Dapivirine Intravaginal Ring for HIV Prevention Among Adolescent Girls and Young Women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 Study)

This journal article from PLOS ONE explored baseline preferences for oral PrEP or the dapivirine ring for AGYW (adolescent girls and young women) in South Africa, Uganda, and Zimbabwe.

Monitoring & Evaluation

External Link
13 March 2023

PrEP Use and HIV Seroconversion Rates in Adolescent Girls and Young Women from Kenya and South Africa: The POWER demonstration project

This article from the Journal of the International AIDS Society describes the POWER project, a prospective implementation science evaluation of PrEP delivery for adolescent girls and young women in family planning clinics in Kisumu, Kenya and youth and primary healthcare clinics in Cape Town and Johannesburg, South Africa.

Research, Service Delivery

External Link
6 March 2023

What Motivated Men to Start PrEP? A cross-section of men starting PrEP in Buffalo City Municipality, South Africa

This article from BMC Public Health discusses the results of qualitative interviews with cisgender, heterosexual men initiating PrEP in Buffalo City Municipality, South Africa to explore their perceived HIV acquisition risk, prevention needs, and preferences for PrEP initiation.

Demand Creation/Marketing, Research

External Link
27 February 2023

Impact and Cost-effectiveness of the National Scale-up of HIV Pre-exposure Prophylaxis among Female Sex Workers in South Africa: A modelling analysis

This article from the Journal of the International AIDS Society evaluates the impact and cost-effectiveness of South Africa’s national PrEP programme for female sex workers.

Financing & Costing, Research, Service Delivery

External Link
15 February 2023

Incorporating End-users’ Voices into the Development of an Implant for HIV Prevention: A discrete choice experiment in South Africa and Zimbabwe

This article from BMC Women’s Health describes the results of a discrete choice experiment undertaken with adolescent girls and young women in South Africa and Zimbabwe where participants were asked their preferences for a hypothetical HIV prevention implant.

Research

External Link
10 February 2023

PrEPVacc Study

The PrEPVacc trial, taking place in Mozambique, South Africa, Tanzania, and Uganda from 2018 to 2024, combines an evaluation of experimental HIV vaccines and oral PrEP at the same time. The PrEP arm of the trial compares the effectiveness of TDF/FTC (Truvada) with F/TAF (Descovy).

Research

External Link
6 February 2023

Pregnancy and Neonatal Safety Outcomes of Timing of Initiation of Daily Oral Tenofovir Disoproxil Fumarate and Emtricitabine Pre-exposure Prophylaxis for HIV Prevention (CAP016): An open-label, randomised, non-inferiority trial

This article from The Lancet HIV describes the results of a trial to compare pregnancy and neonatal outcomes in women exposed and not exposed to oral PrEP (TDF/FTC) during pregnancy in Durban, South Africa.

Research

External Link
13 January 2023

Differentiated HIV Services for Transgender People in Four South African Districts: Population characteristics and HIV care cascade

This article from the Journal of the International AIDS Society describes a differentiated service delivery model across four South African sites and transgender individuals who access these services. It assesses whether hormone therapy is associated with continued use of PrEP and viral load suppression.

Research, Service Delivery

External Link
21 December 2022

Adherence Challenges with Daily Oral Pre-exposure Prophylaxis during Pregnancy and the Postpartum Period in South African Women: A cohort study

This article from the Journal of the International AIDS Society explores pharmacologic measures of PrEP adherence during pregnancy and postpartum and the factors related to optimal adherence during periods of sexual activity in this population.

Research

External Link
21 December 2022

End-user Research in Support of Long-acting Systemic Antiretroviral Delivery Systems: Insights from qualitative research with providers and target users in South Africa

This article from BMC Infectious Diseases describes qualitative research investigating perceptions of and preferences for a long-acting, biodegradable implantable PrEP product designed to address challenges relating to adhering to a daily pill regimen amongst adolescent girls and young women and sex workers in Guateng Province, South Africa.

Research

External Link