Resource Library

Use of the Dapivirine vaginal ring and effect on cervical cytology abnormalities

This study aims to determine if the dapivirine vaginal ring and the ring device alone (flexible silicone matrix polymer) was associated with the development of cervical cytology abnormalities.

Research, Service Delivery

Vaginal Ring Acceptability and Related Preferences among Women in Low- and Middle-income Countries: A systematic review and narrative synthesis

The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). This article outlines a systematic review of VR acceptability, values and preferences among women in low- and middle-income countries (LMIC) to inform further investment and/or guidance on VR use for HIV prevention.

Research

Health Care Providers’ Attitudes toward and Experiences Delivering Oral PrEP to Adolescent Girls and Young Women in Kenya, South Africa, and Zimbabwe

This article describes the results of a cross-sectional qualitative study, interviewing providers at public, private, and nongovernmental health facilities in Kenya, South Africa, and Zimbabwe offering PrEP to explore providers’ attitudes toward and experiences delivering PrEP to AGYW.

Research, Service Delivery

Dapivirine vaginal ring for HIV prevention: modelling health outcomes, drug resistance and cost-effectiveness

A vaginal ring containing dapivirine is effective for HIV prevention as pre-exposure prophylaxis (PrEP). The authors of this article evaluated the potential epidemiological impact and cost-effectiveness of dapivirine vaginal ring PrEP among 22- to 45-year-old women in KwaZulu-Natal, South Africa.

Research, Service Delivery

Adoption of guidelines on and use of oral pre-exposure prophylaxis: a global summary and forecasting study

Widespread adoption of WHO PrEP recommendations coincided with a global increase in PrEP use. Although the 2020 global PrEP target will be missed, strong future growth in PrEP use is possible. New PrEP products could expand the PrEP user base, and, with greater expansion of oral PrEP, further adoption of WHO PrEP recommendations, and simplified…

Normative Guidance/Policies, Research, Service Delivery

Health system adaptations and considerations to facilitate optimal oral pre-exposure prophylaxis scale-up in sub-Saharan Africa

Countries in sub-Saharan Africa have progressively scaled up oral PrEP as part of combination HIV prevention. Initial scale-up efforts have generated progress, drawing lessons from existing HIV interventions, such as antiretroviral therapy and biomedical prevention. However, beset by unprepared health systems, scale-up has been slow. This review synthesises literature on essential considerations for PrEP scale-up,…

Normative Guidance/Policies, Research, Service Delivery

AGYW’s PrEP-user Journey During an Implementation Science Study in South Africa and Kenya

Journal article appearing in PLOS ONE examining adolescent girls and young women's experience with oral PrEP in South Africa and Kenya. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community.

Research

A Pilot Evaluation of Expedited Partner Treatment and Partner HIV Self-testing Among Adolescent Girls and Young Women Diagnosed with Chlamydia trachomatis and Neisseria gonorrhoeae in Kisumu, Kenya

This article describes a pilot study among young women receiving PrEP who were diagnosed with Chlamydia trachomatis or Neisseria gonorrhoeae which found high acceptability and uptake of expedited partner treatment and partner HIV self-testing.

Research, Testing

Cost of Pre-exposure Prophylaxis Delivery in Family Planning Clinics to Prevent HIV Acquisition Among AGYW in Kisumu, Kenya

There is need for evidence on the cost of PrEP in real-world implementation to inform the budget impact, cost-effective- ness, and financial sustainability of PrEP programs. This research article elaborates on the cost of pre-exposure prophylaxis delivery in family planning clinics to prevent HIV acquisition among adolescent girls and young women in Kisumu, Kenya

Financing & Costing, Research

Uptake and Impact of Facility-based HIV Self-testing on PrEP Delivery: a pilot study among young women in Kisumu, Kenya

HIV testing is a required part of delivery of pre-exposure prophylaxis (PrEP) for HIV prevention. However, repeat testing can be challenging in busy, under-staffed clinical settings, which could negatively impact PrEP uptake and continuation. This research article discusses findigs on uptake and impact of facility-based HIV self-testing on PrEP delivery from a pilot study among…

Research, Testing