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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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4 March 2024

Estimating the Costs and Perceived Benefits of Oral Pre-exposure Prophylaxis (PrEP) Delivery in Ten Counties of Kenya: A costing and a contingent valuation study

This article from Frontiers in Reproductive Health describes the results of a study to calculate the actual costs of oral PrEP scale-up in ten counties in Kenya, including a comparison of service delivery models across regions. In addition, the study looked at factors that indicate why some individuals place a greater value on PrEP than…

Financing & Costing, Research

External Link
4 March 2024

HIV Preexposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate Among Cisgender Women

This article from the Journal of the American Medical Association describes the results of a pooled analysis to measure HIV incidence among cisgender women with different adherence trajectories to oral PrEP with TDF/FTC.

Research

External Link
22 February 2024

Barriers and Facilitators to Utilizing HIV Prevention and Treatment Services among Migrant Youth Globally: A scoping review

This article from PLOS Global Health describes the results of a scoping review looking at barriers and facilitators for migrant youth to access HIV prevention and treatment services globally.

Research, Service Delivery

External Link
6 February 2024

Impact of HIV Self-testing for Oral Pre-exposure Prophylaxis Scale-up on Drug Resistance and HIV Outcomes in Western Kenya: A modelling study

This article from The Lancet HIV describes the results of a modelling exercise to evaluate the impact of HIV self-testing on oral PrEP scale-up and HIV drug resistance.

Research

External Link
31 January 2024

Creating Allies: Qualitative exploration of young women’s preferences for PrEP methods and parents’ role in PrEP uptake and user support in urban and rural Zambia

This article from BMC Women’s Health describes the results of a qualitative study to learn about PrEP method preferences amongst adolescent girls and young women and their parents in Zambia.

Research, Service Delivery

External Link
22 January 2024

Factors Influencing the Uptake of a Mono-PrEP Implant for the Prevention of HIV: Males’ perspectives from three South African provinces

This article from PLOS One describes the results of a study which aimed to estimate the potential uptake of a mono-PrEP implant and the factors influencing uptake among males in South Africa. The study also examined messaging and demand creation tactics that males perceive will improve HIV prevention uptake.

Demand Creation/Marketing, Research

External Link
22 January 2024

Breaking Down Relationship Barriers to Increase PrEP Uptake and Adherence among Adolescent Girls and Young Women in Kenya: Safety and preliminary effectiveness results from a pilot cluster-randomized trial

This article from Journal of the International AIDS Society describes the impact of the Tu’Washindi intervention, which aimed to increase PrEP use by addressing relationship- and violence-related barriers among adolescent girls and young women enrolled in the DREAMS Initiative in Siaya County, Kenya.

Demand Creation/Marketing, Research, Service Delivery

External Link
22 January 2024

A Community-based Dynamic Choice Model for HIV Prevention Improves PrEP and PEP Coverage in Rural Uganda and Kenya: A cluster randomized trial

This article from Journal of the International AIDS Society describes the effect of a dynamic choice model for HIV prevention, delivered by community health workers with clinician support, on the use of biomedical prevention (including PrEP and PEP) amongst persons at risk of HIV in rural Kenya and Uganda. This research was undertaken as part…

Research, Service Delivery

External Link
14 November 2023

Journal of Adolescent Health Special Issue: Lessons Learned in Providing PrEP for HIV for Adolescents and Young People at Scale

This special supplement of the Journal of Adolescent Health combines 11 scientific articles and two commentaries highlighting PrEP implementation studies among Brazil and South Africa adolescents and youth. These articles highlight the unique HIV vulnerabilities and PrEP barriers experienced by youth in these countries and the implementation strategies required to address these barriers. Five articles…

Research

External Link
14 November 2023

Efficacy and Safety of Long-Acting Cabotegravir Compared with Daily Oral Tenofovir Disoproxil Fumarate Plus Emtricitabine to Prevent HIV Infection in Cisgender Men and Transgender Women who Have Sex with Men 1 Year after Study Unblinding: A secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial

This article from The Lancet HIV describes findings from the first unblinded year of the HIV Prevention Trials Network (HPTN) 083 study, which compared safety and efficacy of cabotegravir and tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as HIV prevention for transgender women and men who have sex with men in Argentina, Brazil, Peru, South Africa, Thailand, the…

Research

External Link