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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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7 November 2023

How Might We Motivate Uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers

This article from Frontiers in Reproductive Health describes the results of a study to identify barriers and motivators for Dual Prevention Pill (DPP) uptake to inform the development of a DPP demand generation strategy and broader introduction efforts for Multipurpose Prevention Technologies.

Research

External Link
6 November 2023

Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial

This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.

Research

External Link
19 October 2023

Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool

This article from Global Health: Science and Practice describes the results of a study to investigate the impact of the Healthy Relationships Tool, part of the CHARISMA Toolkit, on PrEP adherence amongst women in Johannesburg, South Africa.

Research

External Link
9 October 2023

PrEPare_Morocco: A Successful Community-based PrEP Delivery Demonstration Program for Men who Have Sex with Men and Female Sex Workers in Morocco

This article from AIDS Care describes the first PrEP demonstration project in the Middle East/North Africa region, which aimed to assess the feasibility and acceptability of a community-based PrEP program for female sex workers and gay and bisexual men who have sex with men in Morocco’s highest HIV prevalence cities: Agadir, Marrakech, and Casablanca.

Research

External Link
9 October 2023

Efficacy, Safety, Tolerability, and Pharmacokinetics of Long-acting Injectable Cabotegravir for HIV Pre-exposure Prophylaxis in Transgender Women: A secondary analysis of the HPTN 083 trial

This article from the Lancet HIV discusses the results of a secondary analysis of data from the HPTN 083 trial of cabotegravir for PrEP, looking specifically at the cohort of transgender women included in the study.

Research

External Link
6 October 2023

Integrating HIV Preexposure Prophylaxis With Community-Based Syringe Services for Women Who Inject Drugs: Results from the Project SHE demonstration study

This article from Implementation Science describes the results of a demonstration project in Philadelphia, PA, USA to integrate PrEP provision into a syringe services programme for women who inject drugs.

Research, Service Delivery

Document
29 August 2023

Changes in Relationships, HIV Risk, and Feelings towards PrEP: Findings from a qualitative explanatory study among participants in the CHARISMA intervention trial

This article from BMC Women’s Health explores women’s experiences with the CHARISMA randomized controlled trial, which tested whether the CHARISMA intervention mitigated relationship-based challenges to PrEP use, such as intimate partner violence, and looks into why the trial showed null results. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
21 August 2023

Development of a Relationship Counselling Website to Identify and Mitigate Risk of Intimate Partner Violence in the Context of Women’s PrEP Use

This article from PLOS Digital Health discusses the results of beta-testing CHARISMA mobile, a digital resource to support lay counsellors help women access PrEP safely and and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
10 August 2023

Shaping and Coordinating the Implementation Science Agenda for Injectable Cabotegravir for PrEP: The role of the Biomedical Prevention Implementation Collaborative (BioPIC)

This article from JIAS describes the coordinated approach taken by the Biomedical Prevention Implementation Collaborative (BioPIC) to ensure questions regarding delivery of cabotegravir (CAB) for PrEP are addressed so that CAB can be introduced in low- and middle-income countries in timely, acceptable and effective ways.

Research

External Link
10 August 2023

Counterfactual Estimation of Efficacy against Placebo for Novel PrEP Agents Using External Trial Data: Example of injectable cabotegravir and oral PrEP in women

This article from JIAS uses estimated prevention efficacy against a counterfactual placebo to provide information on the use of cabotegravir for PrEP and oral PrEP compared to no intervention.

Research

External Link