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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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4 August 2022

An Implementation Model for Scaling up Oral Pre-exposure Prophylaxis in Kenya: Jilinde project

In this article, the authors describe the conceptual design of the Jilinde project, which implemented oral PrEP as a routine service at a public health scale in Kenya. The authors describe the overlapping domains of supply, demand, and government and community ownership, which combine to produce a learning laboratory environment to explore the scale-up of…

Research, Service Delivery

External Link
4 August 2022

Coordinating Implementation Science for CAB for PrEP

As implementation studies for injectable cabotegravir (CAB) for PrEP are being considered and as programs shift towards choice-based models for HIV prevention, there is a chance to correct for missed opportunities with oral PrEP rollout, understand client preferences and patterns of use, and ensure more effective coordination across geographies, populations, and projects. To facilitate this…

Research

Document
4 August 2022

BioPIC CAB for PrEP Study Compendium

This compendium provides detail on planned and ongoing studies related to landscaping, product introduction, introduction studies, and implementation research for Cabotegravir for PrEP and is a companion to the Implementation Study Tracker. If you would like to add your study to the compendium, please contact Catherine Verde Hashim.

Research

Presentation
21 July 2022

Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study

The Ring Study, a phase 3 trial, showed a favourable safety profile and a 31% HIV infection risk reduction for a vaginal ring containing 25 mg of dapivirine, compared with a placebo ring. This article outlines the DREAM study, which aimed to evaluate safety, adherence, and HIV incidence in those using the dapivirine vaginal ring…

Research

External Link
14 July 2022

Social and Behaviour Change Communication Strategy for Sexual & Reproductive Health, Rights & HIV in Lesotho 2020-21 to 2022-23

Lesotho's Social and Behaviour Change Communication Strategy is a strategic response to the high levels of HIV and TB prevalence in the country that are exacerbated by the persistence of structural and sio-economic difficulties, such as poverty, unemployment, gender inequality and more. This strategy aims to address these issues.

Research, Normative Guidance/Policies

Document
7 July 2022

Health Care Providers as Agents of Change: Integrating PrEP with other sexual and reproductive health services for adolescent girls and young women

Providing integrated HIV PrEP and sexual reproductive health (SRH) care is difficult for many healthcare providers. They face many barriers. Successul integration will require interation and adaptation. O'Malley et al. investigate the structural and motivational barriers that healthcare providers face in providing integrated care to adolescent girls and young women (AGYW).

Research, Service Delivery

External Link
7 July 2022

A community-based mobile clinic model delivering PrEP for HIV prevention to adolescent girls and young women in Cape Town, South Africa

This study explores the feasibility and acceptability of providing PrEP to adolescent girls and young women via a community-based mobile health clinic known as the Tutu Teen Truck in Cape Town, South Africa

Research, Service Delivery

External Link
7 July 2022

Sexually Transmitted Infections Among African Women: An opportunity for combination sexually transmitted infection/HIV prevention

The global epidemic of Sexually Transmitted Infections (STIs) in women demands new prevention approaches. This article outlines new strategies which are emerging that offer opportunities for research and program delivery of combination STI/HIV prevention .

Research

External Link
7 July 2022

Dapivirine Vaginal Ring for HIV Prevention: Modeling health outcomes, drug resistance and cost‐effectiveness

This paper evaluates the potential epidemiological impact and cost-effectiveness of dapivirine vaginal ring PrEP among 22- to 45-year-old women in KwaZulu-Natal, South Africa.

Financing & Costing, Research

External Link
7 July 2022

From Proof-of-Concept to Prevention Phenomenon in Five Years

This timeline, first appearing in AVAC Report 2014/15: HIV Prevention on the Line, shows PrEP going from proof-of-concept to prevention phenomenon in five years and can be used to anticipate and speed action on the next generation of ARV-based prevention options.

Research

External Link